Analytics

Catherine Liloia, Catherine.Liloia@ppd.com, is director at PPD Laboratories’ GMP cell lab.

Benjamin Ziehr, PhD, is senior group leader at PPD Laboratories’ GMP cell lab.

Derrick McVicker, PhD, is group leader at PPD Laboratories’ GMP cell lab.

Yat Yee Wong, PhD, is group leader at PPD Laboratories’ GMP cell lab.

Esteban Carrillo, PhD, is senior research scientist at PPD Laboratories’ GMP cell lab.

Alexander Rodriguez, PhD, is research scientist at PPD Laboratories’ GMP cell lab.

Articles

Developing bioassay methods requires a new approach for cell and gene therapy drug development.

Analytical Strategies for Cell and Gene Therapy Development

Chalmers University researchers have developed a method to label and track mRNA molecules.

Chalmers Researchers Develop Fluorescence Method to Track RNA

Felicity Thomas is Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Outsourcing method development offers multiple benefits to companies, including access to experience and expertise, streamlined costs, and development time efficiencies.

Developing a Method for Success through Partnerships

Mark White, PhD, is associate director, Biopharma Product Marketing, at Bio-Rad Laboratories.

The sensitivity of droplet digital PCR helps manufacturers detect Mycoplasma contamination in AAV-based gene therapy products.

Using ddPCR to Detect Mycoplasma Contamination

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Mass spectrometry and automation are growing in importance for protein characterization, but further improvements are still needed.

Evolving Analytical Technology Unravels Protein Characteristics

Phil Borman, DSc, has served in multiple quality-related roles at GlaxoSmithKline; as of April 2021, he is senior fellow and director of product quality.

Timothy Schofield is owner and consultant, CMC Sciences, LLC;

David Lansky, PhD, is president, Precision Bioassay, Inc.

A well-chosen replication strategy can effectively reduce the uncertainty for an analytical method, enabling appropriate decisions regarding pharmaceutical quality. 

Reducing Uncertainty of an Analytical Method through Efficient Use of Replication

Despite its importance in drug development, dissolution testing still has some limitations, but advances in automation and real-time monitoring are producing promising results.

Limitations and Advances in Dissolution Testing

Garima Thakur is a graduate student in the Department of Chemical Engineering at the Indian Institute of Technology New Delhi.

Anurag S. Rathore is a professor in the Department of Chemical Engineering at the Indian Institute of Technology Delhi and a member of BioPharm International's Editorial Advisory Board, Tel. +91.9650770650, asrathore@biotechcmz.com.

The need for real-time monitoring and control has spurred the development of new analytical tools.

Near Infrared Spectroscopy as a Versatile PAT Tool for Continuous Downstream Bioprocessing

The companies intend to design and implement algorithms for the early stages of research for drug discovery and development of drug candidates to treat Alzheimer’s disease.

Roche and Cambridge Quantum Computing Use Algorithms for Early Alzheimer's Drug Research

The new ultra-sensitive second-generation micro-chip technology is a key enabler in advanced single-cell proteomics workflow.

Analytical Method Development