There is a great need for sensitive, precise, and easily accessible analytical detection techniques for protein sequencing.

Biologics Quality Control: The Growing Need for Accessible Proteomics

The emergence of mRNA vaccines and cell and gene therapies has pushed innovation in analytical methods.

Emerging Therapies Drive Analytical Advancements

Effective analytics will eliminate failures, deviations, and non-conformances.

 Analyzing Exabytes

Topic

Joanne Ratcliff, PhD, is communications project manager, Laboratory Weighing, Mettler Toledo GmbH, Joanne.Ratcliff@mt.com.

Martin Huber, PhD, is head of the GWP competence center at Mettler Toledo, Martin.Huber@mt.com

Articles

The latest revisions to the USP General Chapters <41> Balances and <1251> Weighing on an Analytical Balance aim to ensure weighing accuracy and eliminate unnecessary overtesting by simplifying previous descriptions and reflecting current state-of-the-art weighing practices.

Complying with Revised Weighing Guidelines

Developments in chromatography column technology to deliver greater efficiency, speed and inertness benefit the drug development process from discovery to manufacturing and quality control.

Innovations and Future Trends in HPLC Column Technology

Paul Kippax is a product manager, Laser Diffraction, Malvern Instruments Ltd., Enigma Business Park, Grovewood Road, Malvern Worcestershire, UK WR14 1XZ, Paul.Kippax@malvern.co.uk.

Paul Davies is global business manager for Malvern Instruments.

A diverse range of particle sizing solutions is available, from techniques for the characterization of complex formulations through to online PAT tools for real-time measurement.

Advances in the Pharmaceutical Industry Have Shaped Particle Sizing Technology

Contract research, development, and manufacturing organizations invested in new facilities and technologies in 2014 for analytical testing, as well as small- and large-molecule drug development.

Contractors Invest in Capacity and Capabilities

Experts from contract testing laboratories and service organizations shared their perceptions of analytical testing advances, and challenges still ahead.

Analytical Labs Strive to Deliver More Information, Faster

Shimadzu?s Nexera MP UHPLC Front End system for LC/MS is perfect for LC/MS analysis conducted in pharmacokinetics and synthesis stages in drug detection processes.

The Nexera MP UHPLC for LC/MS analysis in drug detection processes

Thomas A. Little is president, Thomas A. Little Consulting and BioAssay Sciences, 12401 North Wildflower Lane, Highland, Utah 84003, USA, drlittle@dr-tom.com.

The right approach can provide a clear, statistically defendable method for determining dissolution and accelerated stability.

Multifactor Non-linear Modeling for Accelerated Stability Analysis and Prediction

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

The Modular Automated Sampling Technology platform allows sampling of bioreactors.

Automating Online Sampling of Bioprocesses

The YSI Sitini Online Sampler draws fluids from a bioreactor and delivers the samples to an analyzer.

Xylem Laboratory System Enables Online Monitoring and Control of Bioreactors

Nattamai Bhuvanesh is manager of the X-ray Diffraction Laboratory in the Department of Chemistry at Texas A&M University, College Station, TX.

Joseph H. Reibenspies, PhD, is associate director, of the X-ray Diffraction Laboratory in the Department of Chemistry at Texas A&M University, College Station, TX, j-reibenspies@tamu.edu.

Specimen mounting in x-ray powder diffraction affects peak positions and intensities.

Analytics

Biologics Quality Control: The Growing Need for Accessible Proteomics

Emerging Therapies Drive Analytical Advancements

Analyzing Exabytes