There is a great need for sensitive, precise, and easily accessible analytical detection techniques for protein sequencing.

Biologics Quality Control: The Growing Need for Accessible Proteomics

The emergence of mRNA vaccines and cell and gene therapies has pushed innovation in analytical methods.

Emerging Therapies Drive Analytical Advancements

Effective analytics will eliminate failures, deviations, and non-conformances.

 Analyzing Exabytes

Topic

Patrick Bennett is Strategic Marketing Director - Pharma for Thermo Fisher Scientific.

David Horn is senior program manager at Thermo Fisher Scientific, San Jose, CA, USA.

Hongxia (Jessica) Wang is senior marketing specialist at Thermo Fisher Scientific, San Jose, CA, USA.

Zhiqi Hao is biopharma program manager at Thermo Fisher Scientific, San Jose, CA, USA.

Yi Zhang is senior marketing specialist at Thermo Fisher Scientific, San Jose, CA, USA.

Articles

The authors discuss the development of a simple, sensitive, and universal platform for identification and quantification of trace-level protein impurities in biotherapeutics.

Identification and Quantification of Trace-Level Protein Impurities

Tadayuki Yamaguchi, Shimadzu Scientific Instruments

The authors present an analysis of ibuprofen based on United States Pharmacopeia General Chapter  “Chromatography” using high-performance liquid chromatography.

Ultra-High-Speed Analysis of Ibuprofen Using HPLC

Harald Fischer is with WITec, Ulm, Germany.

The authors describe how a combination of imaging techniques can be used to provide topographic and chemical information to characterize a sample.

Characterization with Atomic Force Microscopy, Topographic, and 3D Raman

Chris Burgess, PhD, is an analytical scientist at Burgess Analytical Consultancy Limited, ‘Rose Rae,’ The Lendings, Startforth, Barnard Castle, Co Durham, DL12 9AB, UK; Tel: +44 1833 637 446; chris@burgessconsultancy.com; www.burgessconsultancy.co

The author discusses the purpose of analysis and testing and the implications for specifications and their underlying statistical distribution.

Evaluating Risk-Based Specifications for Pharmaceuticals

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Understanding the supply-chain challenge and coupling high-efficiency chromatographic techniques with information-rich detectors are leading to improvements in the management of extractables and leachables in parenteral drugs.

Experts from Novo Nordisk, Baxter Discuss Technological Advances in Addressing the Challenge of Extractables and Leachables

Greater sophistication in 3D X-ray imaging technology raises its utility for QA/QC in manufacturing.

Addressing Manufacturing Challenges with Nondestructive X-Ray Imaging

Agilent Technologies Inc. introduced the MassHunter BioConfirm application, which allows users to rapidly create targeted screening methods.

Mass Spec Software Optimizes Biopharmaceutical Characterization

Bruker Chemical and Applied Markets offers three LC-triple quadrupole (LC-TQ) mass spectrometers, the EVOQ Qube, the EVOQ Elite, and the EVOQ Elite ER.

Bruker Offers LC Triple Quadrupole Mass Spectrometers

Thermo Fisher Scientific Inc. introduced the Thermo Scientific Orbitrap Fusion Tribrid liquid chromatography-mass spectrometry (LC-MS) system, which combines three mass analyzers.

Thermo Fisher Scientific Launches Tribrid LC-MS

Click chemistry has become a powerful tool in drug discovery, chemical biology, and proteomic applications.

Analytics

Biologics Quality Control: The Growing Need for Accessible Proteomics

Emerging Therapies Drive Analytical Advancements

Analyzing Exabytes