There is a great need for sensitive, precise, and easily accessible analytical detection techniques for protein sequencing.

Biologics Quality Control: The Growing Need for Accessible Proteomics

The emergence of mRNA vaccines and cell and gene therapies has pushed innovation in analytical methods.

Emerging Therapies Drive Analytical Advancements

Effective analytics will eliminate failures, deviations, and non-conformances.

 Analyzing Exabytes

Topic

Articles

In this case study of amines, the authors discuss several parameters to be considered in developing a headspace GC method.

Experimental Considerations in Headspace Gas Chromatography

The growth of Brazil's generic-drug market is on a fast track, but what are the projections for the sector's future?

Report from Brazil May 2010

Enterprise-Level Change Control

When vessels, seals, and cooling units go haywire, operators must get in the mix.

Mixed Blessings

The author proposes techniques, based on Six Sigma methods, for monitoring such processes to discover their airflow patterns and reduce opportunities for spillage.This article is part of PharmTech's supplement "Solid Dosage and Excipients 2010."

Spillage Prevention and Airflow-Pattern Monitoring for High-Shear Process Operations

Rob Darrington is Marketing & Business Development Manager at Genevac.

Sample preparation before analysis is just as important as the analytical technique because poor sample preparation alters or skews the analytical result.

Industry must improve sample preparation techniques

Tim Freeman is Managing Director of powder characterization company Freeman Technology for whom he has worked since the late 1990s. He was instrumental in the original design and continuing development of the FT4 Powder RheometerÂ® and through his work with various professional bodies, and involvement in industry initiatives, is an established contributor to wider developments in powder processing.Tim has a degree in Mechatronics from the University of Sussex in the UK. He is a mentor on a number of project groups for the Engineering Research Center for Structured Organic Particulate Systems in the US and a frequent contributor to industry conferences in the area of powder characterisation and processing. A past Chair of the American Association of Pharmaceutical Scientists (AAPS) Process Analytical Technology Focus Group Tim is a member of the Editorial Advisory Board of Pharmaceutical Technology and features on the Industry Expert Panel in European Pharmaceutical Review magazine. Tim is also a committee member of the Particle Technology Special Interest Group at the Institute of Chemical Engineers, Vice-Chair of the D18.24 sub-committee on the Characterization and Handling of Powders and Bulk Solids at ASTM and a member of the United States Pharmacopeial (USP) General Chapters Physical Analysis Expert Committee (GC-PA EC).

The needs of the pharmaceutical industry for powder testing technologies are changing, primarily for two reasons. The first is that global economics, and the economics and competitiveness of the pharmaceutical industry itself, are driving manufacturers towards achieving greater efficiency.

Understanding powder behaviour

Ana Rita Pires is a PhD student at the University of Porto (Portugal).

D. López Malo is junior researcher at the Department of Analytical Chemistry, University of Valencia (Spain).

J. Martínez Calatayud is Professor of analytical chemistry at the Department of Analytical Chemistry, University of Valencia (Spain) 

Testing the dissolution rates of a pharmaceutical formulation (also known as in vitro availability) aids drug quality control and is a compulsory requirement of the British, European and US pharmacopoeias.

Obtaining simultaneous multiple dissolution profiles of solid oral dosage formulations

Patrick Bennett is Strategic Marketing Director - Pharma for Thermo Fisher Scientific.

Bioanalysis has migrated from a very general vocation to one that requires more specialisation, particularly in GLP applications.

Analytics

Biologics Quality Control: The Growing Need for Accessible Proteomics

Emerging Therapies Drive Analytical Advancements

Analyzing Exabytes