There is a great need for sensitive, precise, and easily accessible analytical detection techniques for protein sequencing.

Biologics Quality Control: The Growing Need for Accessible Proteomics

The emergence of mRNA vaccines and cell and gene therapies has pushed innovation in analytical methods.

Emerging Therapies Drive Analytical Advancements

Effective analytics will eliminate failures, deviations, and non-conformances.

 Analyzing Exabytes

Topic

Darrell R. Abernethy, MD, PhD, is chief science officer, all at the United States Pharmacopeial Convention, 12601 Twinbrook Parkway, Rockville, MD 20852-1790, tel. 301.816.8184, dra@usp.org

William F. Koch, PhD, is chief metrology officer, USP

Articles

The United States Pharmacopeia emphasizes mechanical calibration and a performance test to esnure integrity of the dissolution procedure.

Inside USP: Metrology and USP Dissolution

Michelle Hoffman, editorial director of Pharmaceutical Technology.

Coming Down the Pike: HDAC inhibitors

Chemical imaging of solid dosage forms has become a powerful analytical tool for the development of solid dosage forms.

New Dimensions in Tablet Imaging

Robert L. Green is a research scientist at Ahura Scientific, Inc., 46 Jonspin Road, Wilmington, MA 01887, tel. 978.657.5555, fax 978.657.5921, bgreen@ ahurascientific.com.

Christopher D. Brown is a director of system analytics and applications, both at Ahura Scientific, Inc.

Using a handheld Raman spectrometer, the authors developed methods for 28 commonly used excipients and active ingredients.

Raw-Material Authentication Using a Handheld Raman Spectrometer

Arvind K. Bansal is an associate professor at the National Institute of Pharmaceutical Education and Research, Sector-67, Phase-X, S.A.S. Nagar, Punjab 160062, India, tel 191 0 172 2214682 87, fax 191 0 172 2214692.

The selection of an appropriate salt form for a potential drug candidate is an opportunity to modulate its characteristics to improve bioavailability, stability, manufacturability, and patient compliance.

Salt Selection in Drug Development

Editors' Picks of Pharmaceutical Science & Technology Innovations; Analytical system provides multiuser capability; Encapsulator aids dosage design; Versatile drive offers quick setup

In the Spotlight March 2008

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The European Union's REACH initiative has the potential to affect the flow of chemicals into the pharmaceutical suppy chain.

A Changing Path in Global Sourcing

Show blasts off this month in Philadelphia with more suppliers, new trends, and real-world solutions.

Guest Editorial: Interphex Focuses on Evolution of the Life Sciences

In the Field: News

My personal experience of lab automation is limited to supervising a peptide synthesiser back in the late 1980s. The machine was eye-wateringly expensive - but it was soon paying its way in terms of productivity and research publications. So if I were a stake-holder in a company pondering whether to invest in a well-designed gadget that could automate a routine operation, I'd say: 'go for it'.

Analytics

Biologics Quality Control: The Growing Need for Accessible Proteomics

Emerging Therapies Drive Analytical Advancements

Analyzing Exabytes