There is a great need for sensitive, precise, and easily accessible analytical detection techniques for protein sequencing.

Biologics Quality Control: The Growing Need for Accessible Proteomics

The emergence of mRNA vaccines and cell and gene therapies has pushed innovation in analytical methods.

Emerging Therapies Drive Analytical Advancements

Effective analytics will eliminate failures, deviations, and non-conformances.

 Analyzing Exabytes

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Articles

LabVantage Solutions’ LabVantage 8.4 is the latest version of the company’s comprehensive laboratory information management system.

Lab Management Solution with Enhanced Data Privacy

HORIBA’s new analytical microscope simultaneously performs elemental analysis and optical observation without destroying samples.

New Microscope Combined Imaging Technology with High Speed Analysis

Daniel N. Hayes is associate principal scientist at Cambrex High Point Analytical Research and Development.

Investigation of peak purity failure during HPLC method validation led to discovery of a co-eluting impurity under the main peak. Spectral analysis, including three-dimensional modelling, was used to characterize the peak, leading to the development of a new HPLC method for analysing impurity content.

Utilizing Spectral Analysis in HPLC Diode Array to Discover Impurities

The TSKgel FcR-IIIA-NPR HPLC column from Tosoh Bioscience is a FcRγ affinity chromatography analysis column suited for the analysis of immunoglobulin G glycoforms.

Affinity Chromatography Analysis Column for Antibody Drugs

The companies will develop a software-connected pipetting system for improved reproducibility and traceability in life-science laboratories.

Andrew Alliance, Sartorius to Collaborate on Pipettes

Kieran O’Connor is Analytical Science and Technology senior chemist at SK biotek, Ireland, kieran.oconnor@sk.com. (formerly Bristol Myers Squibb)

John Wasylyk is senior principal scientist at Bristol-Myers Squibb, USA; john.wasylyk@bms.com

Bob Wethman is senior research scientist II at Bristol-Myers Squibb, USA

Ming Huang is senior research investigator I at Bristol-Myers Squibb, USA

Spectroscopic-based control methods were introduced as equivalent alternative methods, first to a gas chromatographic method to monitor an in-process solvent exchange step and second to a potentiometric titration method to release a process input material for drug substance manufacturing. 

Spectroscopy Facilitates Lean Analysis

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Leveraging vast quantities of analytical data requires digitalization and platform integration. 

Paradigm Shift for Data Analysis and Interpretation

Agnes Shanley is senior editor of Pharmaceutical Technology.

When transferring a method from R&D to quality control, success hinges on discovering where “the best” and “the most reliable” intersect.

Analytical Method Transfer: Don’t Oversimplify

Melanie Zerulla-Wernitz is team leader project & service analytics,Vetter Pharma-Fertigung GmbH & Co. KG.

Novel analytical methods may help biologics manufacturers respond to stricter regulations on particulate matter.


Analysis of Sub-Visible Particles

Formulatrix’s FLO i8 and Flow Axial Seal Tip liquid handlers offer automated transferring.

Analytics

Biologics Quality Control: The Growing Need for Accessible Proteomics

Emerging Therapies Drive Analytical Advancements

Analyzing Exabytes