There is a great need for sensitive, precise, and easily accessible analytical detection techniques for protein sequencing.

Biologics Quality Control: The Growing Need for Accessible Proteomics

The emergence of mRNA vaccines and cell and gene therapies has pushed innovation in analytical methods.

Emerging Therapies Drive Analytical Advancements

Effective analytics will eliminate failures, deviations, and non-conformances.

 Analyzing Exabytes

Topic

Gayatri C.Patel, M.Pharm, PhD, is associate professor in the Department of Pharmaceutics & Pharmaceutical Technology, Ramanbhai Patel College of Pharmacy at the Charotar University of Science and Technology, Changa Campus, Changa- 388 421, Anand, Gujarat, India, gayatripatel.ph@charusat.ac.in, +91 2697 265162.

Chintan Patel is a researcher in the Department of Biotechnology, Zydus Research Centre, Cadila Healthcare Ltd., Ahmedabad, Gujarat, India. 

Sanjay Bandyopadhyay, PhD, is vice-president in the Department of Biotechnology, Zydus Research Centre, Cadila Healthcare Ltd., Ahmedabad, Gujarat, India

Articles

It is important to address manufacturing problems associated with the shorter shelf-life of pegylated L-asparaginase (pegaspargase) upon long-term storage in the form of a solution. 

Degradation Pathways: A Case Study with Pegylated L-Asparaginase

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Confidence in the quality systems and scientific competence of the API manufacturing team is essential.

Select Suppliers with Demonstrated Expertise to Avoid Sourcing “Bad” APIs

Rita Peters is the former editorial director of 

Pharmaceutical Technology, Pharmaceutical Technology Europe

Supplier vetting and monitoring-plus comprehensive testing-ensure quality of raw materials.

Locking Fraudulent Materials Out of the Supply Chain

Beverly Nickerson, PhD, is an associate research fellow in analytical research and development at Pfizer Inc., Eastern Point Road, Mail Stop 4086, Groton, CT 06340, tel. 860.441.0668, fax 860.715.8004, beverly_nickerson@groton.pfizer.com.

Anster Charles was a graduate student at the University of Missouri’s Chemistry Department, Columbia, MO.

Carlos Lee works for Lyndra Therapeutics, Watertown, MA.

Gail Johnson works for Pfizer Worldwide Research and Development in Groton, CT.

John Warzeka works for Pfizer Worldwide Research and Development in Groton, CT.

Laboratory testing found that a novel approach reduced the time required for sample preparation from hours to minutes. This article summarizes test methods and results.

Speeding Sample Preparation and API Extraction from Solid Oral Dosage Formulations

Waters debuted a range of new TA Instruments innovations and the BioAccord System at Pittcon 2019 in Philadelphia, PA, on March 17–21, 2019.

Waters Showcases New TA Innovations and Biopharma System at Pittcon 2019

Katalyst D2D from ACD/Labs enables the design, planning, execution, and analysis of high throughput (HT) experiments. The web-based application was introduced at Pittcon 2019 in Philadelphia, PA.

Web-based Application Automates HT Experimentation at Pittcon 2019

The LenS3 Multi-Angle Light Scattering (MALS) detector, presented at Pittcon 2019 in Philadelphia, PA, uses a new approach for measuring molecular weight and radius of gyration of synthetic polymers, polysaccharides, proteins, and biopolymers.

Tosoh Bioscience Introduces New MALS Detector at Pittcon 2019

Microsaic Systems showcased its new MiD ProteinID point-of-need mass spectrometer at Pittcon in Philadelphia, PA, from March 18–21, 2019.

New Protein Characterization Technique Unveiled at Pittcon 2019

Sartorius introduced the Cubis II portfolio of laboratory balances at Pittcon 2019 in Philaphelia, PA.

Laboratory Balances for Improved Operational Efficiency and Flexibility

Bruker highlighted new analytical systems for several industry applications, including pharma, materials science, and clinical/preclinical research.

Analytics

Biologics Quality Control: The Growing Need for Accessible Proteomics

Emerging Therapies Drive Analytical Advancements

Analyzing Exabytes