Drug Development

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Articles

Particle-engineering technologies, such as crystal design for crystallization and producting cocrystals, particle-size reduction, and amorphous solid dispersions, help to optimize delivery of a drug.

Seeking Solutions in Solid-State Chemistry

Solubilizers play an important role in dissolving poorly soluble molecules. As the number of poorly soluble lipophilic and/or hydrophobic molecules increases-whether as "brick dusts" or waxy substances-the industry is struggling to identify the appropriate lipophilic excipients (surfactants, solubilizers, solvents or polymers) that can be used to develop such poorly soluble formulations into solid dosages and other forms of pharmaceutical products.

Rebranding Lipophilic Excipients

Industry and academia advance novel approaches for achieving enanioselectivity.

Meeting Challenges in Asymmetric Synthesis

Tina S. Morris, PhD, is vice president of Biologics & Biotechnology at United States Pharmacopeia (USP) 

USP optimizes identification tests and impurities procedures.

USP Further Strengthens Quality Standards for Heparin

A Q&A with BASF moderated by Patricia Van Arnum.

Excipients in Tastemasking

The authors explain chemical transformations that are achievable through certain biocatalytic routes.

Making API Synthesis Greener

Approaches to scaling up API syntheses center on ways to optimize process conditions and operability.

Scaling up API Syntheses

Eric Langer has over 25 years experience in biotechnology and life sciences strategic marketing management, market research, and publishing. He has held senior management and marketing positions at biopharmaceutical supply companies. He has published and authored many books and reports on topics in Biotechnology, Large-scale BioManufacturing, and bioscience commercialization and communication. He teaches at Johns Hopkins University marketing management, biotech marketing, services marketing, and marketing in a regulated environment. In 1989 he co-founded BioPlan Associates, Inc. to provide market analysis, and strategy to biotech and healthcare organizations.

Budgets for biopharmaceutical activities are gaining in select functional areas except outsourcing.

Gauging Biopharm Outsourcing

A complete and unedited audio slideshow of the Excipient Fest roundtable on atypical visible particles

Excipient Fest Slideshow and Audio

Flow chemistry and microreactors offer an alternative to traditional batch manufacturing.

APIs and Excipients