Drug Development

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Articles

Potent-compound awareness training for operators is important to understand why the containment and controls are in place. 

Contract Manufacturing Organizations Expand in High-Potency Manufacturing

The debate over functionality is not about to be settled anytime soon. 

Debating Excipient Functionality

Combinatorial catalysis in asymmetric synthesis and asymmetric biaryl Suzuki coupling highlight recent advances in chiral chemistry. Plus the marriage of green and chiral chemistry.

Rolling Out Advances in Chiral Chemistry

Select large custom manufacturers expand capacity, private equity firms buy companies in transition, and players from India and China build their positions. 

Rising Players in Global Fine Chemicals

CMOs account for 20–30% of biopharm production. Big Pharma also is filling the biologics supply chain. 

A Capacity Wave in Biologics Manufacturing

Indian suppliers of active pharmaceutical ingredients and dosage formulations expand in India, the United States, and Europe. 

Asian Producers Raise Their Profiles In the Global Pharmaceutical Value Chain

New biocatalytic and chemocatalytic routes to chiral intermediates and developments in simulated-moving-bed and supercritical-fluid chromatography for resolving racemic mixtures. 

Single-Enantiomer Drugs Drive Advances in Asymmetric Synthesis

Facing still-sluggish market conditions and a changing world order in fine chemicals, the large Western custom manufacturers are responding by building their toolboxes in specialized technologies in chiral chemistry, catalysis, and biosciences and by adjusting their manufacturing networks via streamlining or investment in Asia. 

Custom Manufacturers Target Chiral Chemistry, Catalysis, and Biosciences

This is a year of change for the Synthetic Organic Chemical Manufacturers Association (SOCMA), the Washington, DC-based trade association representing chemical batch and custom manufacturers. Following the sale of Informex, its flagship trade show, last fall, the association is advancing key programs, most notably its new ChemStewards program, an environmental, health, safety, and security initiative (EHS&S) that its members began implementing last month.

SOCMA Launches ChemStewards Program

Palatinit's "galenIQ" is line of multifunctional excipients that offer the combined advantages of other bulk excipients.

APIs and Excipients