APIs and Excipients

Myeloid Therapeutics Gets $73 Million to Advance mRNA-based Pipeline

May 23, 2023

With $73 million in financing from investment firms, Myeloid Therapeutics plans to accelerate its lead clinical candidate into Phase I/II development for treating solid tumors.

Launch of Sania Therapeutics Expected to Advance Development of Novel Therapeutics for Neural Circuit Dysfunction

May 18, 2023

Sania Therapeutics has emerged from stealth mode and launched its technology platforms for enabling the development of novel therapeutics to treat neural circuit dysfunction.

BiOneCure Therapeutics and Nanjing Leads Biolabs Partner to Develop ADCs for Solid Tumors

May 16, 2023

Under the collaboration, BiOneCure Therapeutics and Nanjing Leads Biolabs intend to develop a range of innovative antibody-drug conjugates for treating solid tumors.

Challenges of Expanding CAR-T Cell Therapy into Solid Tumors

May 03, 2023

The development of CAR-T therapies for solid tumor cancers presents a myriad of challenges.

Continuous Hot-Melt Extrusion for Poorly Soluble APIs

May 02, 2023

Process control is essential for using continuous hot-melt extrusion to enhance solubility.

Stability in mRNA-LNP Formulations

April 15, 2023

Lipids aren’t the only important ingredients influencing stability and in vivo performance.

Nucleic Acid-based Therapeutics Are Stepping into the Spotlight

April 15, 2023

The recent success of mRNA vaccines has opened the door for further and future development of nucleic acid-based therapies.

Learning to Think at Lightspeed

April 15, 2023

Actions combatting the next pandemic must be diverse, reliable, and sustainable.

Managing mRNA Instability

April 15, 2023

Unique solutions are required to protect inherently unstable messenger RNA.

The Role of Separation Techniques in the Analysis of mRNA Therapeutic Drug Substances and Drug Products

April 15, 2023

This article reviews a range of techniques available for separative analysis of mRNA therapeutics, their associated impurities, and delivery vehicles.