Drug Development

Articles

Hovione has installed a new MG2 Tekna Precision Capsule filler at its Portugal site.

Hovione Adds New Capsule Filler at Portugal Site

A ceremony was held at Cambrex’s Karlskoga facility to mark the commencement of a long-term manufacturing agreement with AstraZeneca for a key intermediate.

Cambrex and AstraZeneca Mark Long-Term Supply Agreement at Sweden Site

The acquisition, valued at EUR 520 million (US$631 million), would expand Takeda’s late-stage pipeline in gastroenterology and would extend an already existing collaboration between the two companies.

Takeda to Acquire TiGenix

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Graham Reynolds, vice-president and general manager, Global Biologics at West Pharmaceutical Services, Inc., shares insights on key considerations when developing a biologic drug product in a prefilled syringe. 

Formulation and Functional Considerations for Delivering Biologics in Prefilled Syringes

The companies aim to develop a potential zinc finger protein transcription factor-based gene therapy for treating Lou Gehrig’s disease.

Pfizer and Sangamo Partner on Gene Therapy for Lou Gehrig's Disease

The companies aim to discover and develop locked nucleic acid oligonucleotides as orally available therapies for treating inflammatory bowel diseases.

Boehringer Ingelheim and Roche Collaborate on Treatment for Inflammatory Bowel Diseases

The development of new packaging solutions that are fit for drugs of the future requires close collaboration between the pharmaceutical manufacturer and its packaging suppliers and machine vendors.

Elucidating Parenteral Packaging Requirements for Future Drugs

The Wilden Quattroflow QF10k size pump from PSG, a Dover company, has been designed to fill the gap between the existing QF4400/5050 and QF20k pump sizes.

Additional Size for Quaternary Diaphragm Pumps

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

FDA looks to achieve near-record level of new drug approvals following slowdown in 2016.

FDA Ramped Up Approval Rate in 2017

Guy Bouvier, guybouvier06FR@gmail.com, is nonclinical coordination and evaluation manager at Nestle Skin Health. 

Jean-Guy Boiteau is head of process research and development at Nestle Skin Health. 

Amandine Gras is product development coordinator and CMC expert at Nestle Skin Health. 

Anne-Pascale Luzy is head of in vitro toxicology at Nestle Skin Health.

Jean-Pierre Etchegaray is pharmaceutical development expert at Nestle Skin Health.

The authors offer recommendations for permissible daily exposures and concentration limits of elemental impurities for dermal drug products.

APIs and Excipients