APIs and Excipients

Equipment and Processing Report

Removing Aggregates from Monoclonal Antibodies

March 18, 2015

Several chromatographic resins are available for downstream purification.

Assessing and Improving the Palatability of Pharmaceuticals

March 15, 2015

Taste may be subjective, but it is crucial to patient compliance, particularly for pediatric treatments.

Analytical Techniques for Oral Solid Dosage Formulation

March 15, 2015

Analytical technologies must accurately identify and measure the critical material attributes of APIs and excipients.

Boosting Solubility in Lipid-Based Formulations

March 15, 2015

Ionic liquid technologies offer a new way to improve bioavailability.

Using Polymers for More Efficient Hot-Melt Extrusion and Spray Drying

March 15, 2015

New cellulosic polymers have been shown to improve solubility in these key amorphous solid dispersion processes.

Minimizing Risk during HPAPI Manufacture

March 02, 2015

Protecting workers, patients, and the environment requires advanced technologies.

Implementation of ICH Q3D Elemental Impurities Guideline: Challenges and Opportunities

March 02, 2015

Assessing risk factors is key to implementing the new ICH Q3D guidelines for elemental impurities.

Removing Aggregates in Monoclonal Antibody Purification

March 02, 2015

Several chromatographic resins are available for downstream purification.

Considerations for personal protective equipment when handling cytotoxic drugs

March 02, 2015

It is vital that companies involved in the manufacturing and handling of cytotoxic drugs ensure that staff are given the highest possible levels of protection.

Chiral Resolution with and without Resolving Agents

February 02, 2015

Resolution technologies remain crucial for commercial-scale chiral API production.