Analytics

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Articles

NMR analysis provides crucial structural information of synthesized glycans while LC-MS/MS is ideal for quantitation of free sugars in biological matrices.

The Role of NMR and Mass Spectroscopy in Glycan Analysis

F.C. Girard, PhD, is CEO of Spinnovation Analytical.

The author discusses current expectations in bioprocessing and lays a framework for using NMR to enhance a QbD approach.

Nuclear Magnetic Resonance as a Bioprocessing QbD Application

The authors describe the benefits of nuclear magnetic resonance (NMR) compared with traditional monitoring techniques. They also discuss how NMR reaction monitoring provides a new process analytical technology tool for industry.

NMR Reaction-Monitoring as a Process Analytical Technique

Susan J. Schniepp is a fellow at Regulatory Compliance Associates, Inc. and a member of Pharmaceutical Technology's Editorial Advisory Board.

A new book inspires readers to seek ways to apply NMR spectroscopy to their own purposes.

An Analytical Technique with Special Resonance

Michigan State University researchers have discovered a technique for viewing whole cells to gain an understanding of protein inclusion bodies.

NMR Approach May Speed Up Protein-Based Drug Development

Asish B. Chakraborty is a senior scientist at Biopharmaceutical Sciences, Waters Corporation, 34 Maple Street, Milford, MA 01757.

Weibin Chen is a principal research chemist at Biopharmaceutical Sciences, Waters Corporation, 34 Maple Street, Milford, MA 01757.

John C. Gebler is a senior scientist at Biopharmaceutical Sciences, Waters Corporation, 34 Maple Street, Milford, MA 01757.

The authors developed a method to accurately measure the average molecular weight of large poly(ethylene glycols) (PEGs) using ion-mobility time-of-flight mass spectrometry coupled with gas-phase ion–molecule reactions.

Improved Mass Determination of Poly(ethylene glycols) by Electrospray Ion-Mobility Time-of-Flight Mass Spectrometry Coupled with Ion–Molecule Reactions

This article discusses the advantages and disadvantages of using solid-state NMR spectroscopy for the analysis of pharmaceutical solids.

Bio/Pharmaceutical Analysis, NMR