Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Ronald A. Rader is senior director, Technical Research, at BioPlan Associates.

Eric Langer has over 25 years experience in biotechnology and life sciences strategic marketing management, market research, and publishing. He has held senior management and marketing positions at biopharmaceutical supply companies. He has published and authored many books and reports on topics in Biotechnology, Large-scale BioManufacturing, and bioscience commercialization and communication. He teaches at Johns Hopkins University marketing management, biotech marketing, services marketing, and marketing in a regulated environment. In 1989 he co-founded BioPlan Associates, Inc. to provide market analysis, and strategy to biotech and healthcare organizations.

Articles

Advances in techniques and single-use systems are revolutionizing vaccine manufacturing.

Bioprocessing Advances in Vaccine Manufacture

Prequalification of Sanofi Pasteur?s Menomune vaccine makes it eligible for purchase by United Nations agencies.

Sanofi Pasteur's Meningococcal Vaccine is Prequalified by the World Health Organization

Avacta?s Optim 2 instrument provides a practical solution for determining the conformational stability of adjuvant bound vaccines, eliminating the need for awkward and time consuming standard analytical techniques. [more?..]

MEASURING THE PHYSICAL STABILITY OF SUBUNIT VACCINES

Joanne Ratcliff, PhD, is communications project manager, Laboratory Weighing, Mettler Toledo GmbH, Joanne.Ratcliff@mt.com.

George Hartford is laboratory technician/inventory coordinator for labeled compounds in analytical chemistry, Merck Research Laboratories, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ 07065-0900, USA.

Karen Whitaker is senior specialist, Rahway Safety and the Environment, Merck Research Laboratories, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ 07065-0900, USA.

Patty Cheung is associate principle scientist in analytical chemistry, Merck Research Laboratories, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ 07065-0900, USA.

Roy Helmy, PhD, is director of analytical chemistry, all at Merck Research Laboratories, 126 East Lincoln Avenue, P.O. Box 2000, Rahway, NJ 07065-0900, USA.

The advantages of using an automated powder dispensing system in a ventilated balance enclosure for efficient handling and effective containment of potent compounds are discussed.

Effective and Efficient Weighing of Potent Compounds

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Industry experts discuss the requirements and challenges involved in getting a biosimilar product from bench to launch.

The Importance of Characterization in Biosimilars Development

The Bosspak VTC 100 electronic tablet and capsule counter from Romaco?s is designed to fill pharmaceutical solids or food supplements into bottles at high speed.

Bosspak VTC 100 Tablet and Capsule Counter

Conrad Winters, PhD, is director, Drug Product Development Group, Hovione FarmaCiencia SA.

Filipe Neves, PhD, is group leader, Drug Product Development Group, Hovione FarmaCiencia SA.

Case studies on the manufacture of a bluk powder and the development of a tablet show the application of QbD principles.

Optimizing Quality by Design in Bulk Powders and Solid Dosage

A Sanofi Pasteur flu-vaccine trial in adults 65 years of age and older meets a primary endpoint for superior efficacy.

Sanofi Pasteur's High-Dose Flu Vaccine Shows Superior Clinical Benefit in Older Adults

FDA's draft guidance provides answers to questions received on FDA's abbreviated new drug application stability guidance.

FDA Publishes Draft Questions and Answers to Generic-Drug Stability Testing Guidance

Conventional cell-imaging systems that provide high quality data can be expensive and complex to use. New systems from Biotek Instruments are designed to overcome these issues.