Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Stephanie Sutton was an assistant editor at Pharmaceutical Technology Europe.

Articles

Novartis has completed the acquisition of a majority stake in Zhejiang Tianyuan Bio-Pharmaceutical Co., Ltd. &#151; one of the largest privately held vaccines companies in China.

Novartis Acquires Chinese Vaccine Company

Novartis acquired a majority stake in Zhejiang Tianyuan Bio-Pharmaceutical, one of the largest privately held vaccine companies in China. The acquisition gives Novartis an expanded presence in the Chinese vaccine market and will facilitate the introduction of Novartis's vaccines into the country.

Japan has suspended the use of two pediatric vaccines made by Pfizer and sanofi following the deaths of four children in three days.

Japan Halts Use of Pfizer and sanofi Vaccines

Steve Boswell is Director at S3 Process Ltd., Tel. +44 (0) 7891485368, 

Geoff Smith is Reader at Pharmaceutical Technologies Group, Leicester School of Pharmacy, De Montfort University (UK).

Although tablet manufacture is traditionally a batchbased wet granulation process, there are many advantages to be gained by adopting dry granulation, including lower costs and increased yields.

Improving Solid Dosage Forms With Dry Granulation

Steve Deakin is Business Development Director at I Holland.

Tooling standardisation in the tablet manufacturing industry is a topic that has concerned tabletting professionals for decades.

The Benefits Of Tablet Tooling Standardisation

With a regulatory pathway for follow-on biologics, industry is wondering what FDA will do next.

Next Steps for the US Biosimilar Regulatory Scheme

The authors evaluated the manufacturing data of 40-mg tablets of furosemide, a potent diuretic.

A Statistical Approach to Evaluating the Manufacture of Furosemide Tablets

A single, global tooling standard would offer many benefits, but one has been slow to emerge.

The Benefits of Tablet Tooling Standardization

Anurag S. Rathore is a professor in the Department of Chemical Engineering at the Indian Institute of Technology Delhi,  Tel. +91.9650770650, asrathore@biotechcmz.com.

The author provides an overview of QbD implmentation for biopharmaceuticals.

Quality by Design for Biologics and Biosimilars

The authors outline the key decision points FDA must consider in putting forth a US regulatory pathway for biosimilars.