Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Angie Drakulich was editorial director of Pharmaceutical Technology.

Articles

The US Food and Drug Administration withdrew this week its direct final rule on Reporting Information About Authorized Generic Drugs.

Final Rule for Generic Reporting Withdrawn

During the past years, there has been increasing demand for fast dissolving disintegrating tablets (FDDTs), such as orally disintegrating tablets (ODTs) and sublinguals.

Fast dissolving disintegrating tablets with isomalt

A discussion of the basic principles of immunity and the nature of antibodies.

Understanding immunogenicity responses

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The US Department of Health and Human Services's Biomedical Advanced Research and Development Authority has awarded Novartis a contract valued up to $486 million over eight years to support the design, construction, validation, and licensing of a US cell-based influenza vaccine manufacturing facility in Holly Springs, North Carolina.

HHS Awards Novartis Vaccine Contract

Outsourcing sterile manufacturing involves an integrated approach in product life-cycle management.

Life-Cycle Management for Sterile Drugs

Carl Jones is a production manager (scale-up) at Protherics UK.

Aline Denton is a compliance manager at Protherics UK, Blaenwaun, Ffostrasol, Llandysul, Ceredigion, Wales, UK, SA44 5JT, tel. +44 1239 851 122.

The authors examine the challenges of integrating a large-scale chromatography and nanofiltration process for purification of a polyclonal antibody.

Integration of Large-Scale Chromatography with Nanofiltration for an Ovine Polyclonal Product

The biotechnology sector is occasionally described as a rainbow, with each sub sector having its own colour. But what do the different colours of biotechnology have to offer the pharmaceutical industry?

The four colours of biotechnologyy

A new excipient for orally disintegrating tablets not only imparts superior tablet characteristics, but has the added advantage of allowing users to maintain full control over their formulations, manufacturing processes and intellectual property.

Application-related properties of a new fast dispersible excipient

A new year, all things being equal, is a time of looking to the future with positive intent and traditional bonhomie. At the very least, it suggests new beginnings. As we enter 2009, however, the world is moving into a major recession and things are far from equal.

New beginnings

Reducing ecological footprint and achieving more sustainable production of pharmaceuticals could help create a better future.