Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Johannes G. Khinast is professor at the Institute of Process and Particle Engineering, Graz University of Technology, Austria

Stephan Sacher is senior scientist at the Research Center for Pharmaceutical Engineering GmbH in Graz, Austria.

Elen Gartshein is senior manager at Pfizer Global Supply, Peapack, NJ, USA.

Matthias Wolfgang is scientist at the Research Center for Pharmaceutical Engineering GmbH in Graz, Austria.

Patrick Wahl is senior scientist at the Research Center for Pharmaceutical Engineering GmbH, Graz, Austria.

Articles

Optical coherence tomography can improve quality control and development of coated dosage forms by allowing film thickness to be measured in real time.

Real-Time Measurement of Coating Film Thickness

C-Bridge Capital will form a new biopharmaceutical company, AffaMed Therapeutics, which will collaborate with Samsung Bioepis to accelerate clinical development and registration of Samsung Bioepis’ next-generation biosimilars in China.

Samsung Bioepis and C-Bridge Capital to Commercialize Biosimilars in China

Marc Brown, PhD, is chief scientific officer and co-founder of MedPharm.

Sarah Pratt is chief operating officer at MedPharm.

Christopher Harrison, is head of Process Development and Manufacture at MedPharm.

Using a QbD approach in the development and formulation of topical products will enable the drug developer to provide a robust control strategy for manufacturing.

Process Development Best Practices for Topical Drug Products

Martin Koeberle is head of Analytical Development & Stability Testing, HERMES PHARMA-a division of Hermes Arzneimittel GmbH.

The challenge of achieving sustained delivery of an active ingredient or nutrient can be achieved with extended-release formulations.

A User-Friendly Approach to Developing an Extended-Release Product

Valerie Theobald is director, immunoanalytical services at Charles River Laboratories. 

Jenifer Vija is scientific director, bioanalysis, at Charles River Laboratories.

Jessica St. Charles is director, laboratory sciences at Charles River Laboratories.

Christina Satterwhite, PhD, is senior director, global laboratory sciences at Charles River Laboratories. 

Drug developers must understand the complex bioanalytical assays for cell- and gene-therapy drug development programs and ensure that partners have the specialized expertise needed for complex therapeutic classes.

Emerging Therapies Test Existing Bioanalytical Methods

This injection formulation of USP-grade leucovorin calcium is now available in the United States.

Fresenius Kabi Launches Leucovorin Calcium Injection, USP

Yasvanth Ashokraj works in Integrated Product Development at CIPLA.

Prashant Modak works in Integrated Product Development at CIPLA.

Kalpesh Sawant work in Integrated Product Development at CIPLA.

Praveen Date works in Integrated Product Development at CIPLA.

Swati Laud works in Integrated Product Development at CIPLA.

This article demonstrates how qualitative physical attributes testing can be used to characterize soft gel capsule rupture/disintegration during rectal administration.

Evaluating a New Quality Control Test for Soft Gelatin Rectal Capsules

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Virpax’s Patch-in-a-Can technology delivers pain medication using a metered-dose spray film.

Spray Film Provides Alternative to Patches

Drug and adhesive formulation are crucial to the development of microneedle patches for pharmaceutical transdermal delivery systems. 