Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Vince Russell is director of Respiratory Discovery at Aptuit, www.aptuit.com/drug-design-and-discovery/therapeutic-areas/respiratory.Â 

Articles

Pulmonary drug delivery is becoming increasingly used. When developing pulmonary drugs, pharmaceutical chemists must consider drug absorption, control of particle size, suitable toxicology models, and patient compliance. The author reviews the issues specific to developing drugs designed for pulmonary delivery and considers how-with the right knowledge and expertise-these challenges can be overcome.

Four Challenges for Pulmonary Drug Delivery

Carolina Diaz Quijano, PhD, is manager of Innovation and Technical Marketing Nutra/Pharma at Omya International AG, Baslerstrasse 42, 4665 Oftringen, Switzerland, info.pharma@omya.com.

Functionalized calcium carbonate provides high porosity, which enables fast disintegration, and excellent compactibility that results in harder tablets at low compression forces. 

A Multifunctional Mineral Excipient

The acquisition of Protein Sciences, a vaccines biotechnology company, strengthens Sanofi’s influenza vaccines portfolio.

Sanofi Closes Acquisition of Protein Sciences

FDA halts unproved stem-cell cancer treatments administered to California patients, which was derived from a commercially unavailable military-grade vaccine.

FDA Seizes Military Vaccine Used in Unauthorized Stem-Cell Treatments

Hallie Forcinio is packing editor for Pharmaceutical Technology and Pharmaceutical Technology Europe, editorhal@sbcglobal.net.

Sensors and communication capability support proper usage, improve compliance, and may enable telemedicine. 

Smart Inhalers Improve Patient Compliance

The Thermo Scientific Pharma mini implant line is built around the Thermo Scientific Pharma mini HME twin-screw micro compounder.


Lab Line Is Designed for Developing Drug Implant Technology

Cambrex is investing $24 Million in new, highly potent API manufacturing capacity at its Charles City, Iowa site.

Cambrex Adds HPAPI Capacity

FDA requests more detailed information on a post-marketing study for Dynavax’s hep-B vaccine, which will require an extended review time past its August 2017 PDUFA date.

FDA Extends Dynavax’s Hep B Vaccine Review

Through its life-sciences business, MilliporeSigma, Merck KGaA will collaborate with Baylor College of Medicine to advance vaccine development for neglected and emerging diseases.

Merck KGaA and Baylor Partner on Vaccines for Neglected Diseases

Lonza further expands its micronization services with the acquisition of Swiss contract manufacturer, Micro-Macinazione, following its previous $5.5-billion acquisition of dosage form provider, Capsugel.