Dosage Forms

Reshaping Dosage Forms

Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Frontrunners in Bispecific Antibodies

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Cleaning Bioreactors and Fermenters with CIP Systems

July 02, 2016

Early planning for the integration of clean-in-place systems for equipment cleaning is key.

Exploring the Use of Aseptic Spray Drying in the Manufacture of Biopharmaceutical Injectables

July 02, 2016

Aseptic spray drying provides an alternative to lyophilization as an enabling stabilization technology for parenteral biologic formulations.

Survey Results Explores Biopharma Risk Model

July 01, 2016

A study by MilliporeSigma and the Economist Intelligence Unit reviews growth drivers and approaches to mitigate risk.

Ibrutinib Receives Orphan Drug and Breakthrough Therapy Designation for cGVHD

June 30, 2016

The drug received breakthrough therapy and orphan drug designation as a monotherapy for the treatment of chronic graft-versus-host-disease.

Pre-exposure to Dengue Virus May Predict Reaction to Zika Virus

June 28, 2016

Antibodies to dengue may either confer protective immunity to the Zika virus or enhance disease severity in secondary, related infections such as Zika.

MilliporeSigma Collaborates with International Vaccine Institute

June 28, 2016

MilliporeSigma and the International Vaccine Institute in Seoul, South Korea aim to develop more robust, scalable vaccine manufacturing processes.

Roche’s Ocrelizumab Granted Priority Review

June 28, 2016

The monoclonal antibody for the treatment of two forms of multiple sclerosis has a target action date of December 28, 2016.

EMA Recommends New High-Risk Blood Cancer Therapy

June 24, 2016

The agency recommends Zalmoxis, a new cell-based therapy to support stem cell transplantation in patients with high-risk blood cancer.

Study: HIV-1 Neutralizing Antibodies in Infants May Impact Vaccine Development

June 23, 2016

Studying broadly neutralizing antibodies in infants may lead to new pathways in HIV vaccine development.

CAR-T Optimized to Target Solid Tumors in Animal Models

June 21, 2016

A research team associated with Dr. Carl June announces it has discovered a way to engineer a patient’s own immune cells to recognize cancer-specific glycoantigens on tumor cells.