Accurately targeted immunotherapies through reliable neoantigen recognition enable personalized medicine development.

Research into Cold Cancers Heating Up

Activation and expansion are essential for success in both autologous and allogeneic therapies.

Development of Gamma-Delta T-Cell Therapies

Continuous manufacturing and a quality-by-design development approach are a natural fit.

QbD for Small-Molecule Continuous Process Development

Topic

is regional product manager of Cell Line, Media & Testing Solutions at Sartorius.

Articles

Biopharmaceutical manufacturers must consider a surprisingly wide range of factors when deciding where to turn for assistance with cell line development.

Exploring Options for Optimizing Cell Line Development

Moritz Perscheid is a pharmaceutical chemist at LGC.

It is argued that orthogonal quantitative methods can be used to establish primary working standards. An example details how to calculate the expanded measurement uncertainty (U) for the certified assay value by considering two orthogonal assay methods.

The Value of Primary Working  Standards in Pharmaceutical Quality Control

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

API permeation into the skin modulates the efficacy of topical treatments.

Delivery Kinetics for Topical Drugs

Felicity Thomas is the former Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

It is possible to overcome some of the limitations of traditional dosage forms by employing alternative drug delivery formulation strategies.

Delivering a Difference in Formulation

Cheryl Barton is director of PharmaVision, 

A new unitary patent system is due to come into effect in Europe later on this year.

What Impact Will the New Unitary Patent System Have in Europe

Forecyte Bio and Cytiva will team up to accelerate the development and manufacturing of cell and gene therapies.

Forecyte Bio and Cytiva to Collaborate on Cell and Gene Therapy Manufacturing and Development

Pharmaceutical Technology spoke with Andrew Anderson, Global Head Strategic Account Management and Mary Todas, Director Technical Development and Regulatory Affairs, both with Pfizer CentreOne, about best practices for API quality. 

Industry Perspectives on Quality–A Conversation with Pfizer CentreOne

Scientists have developed a mouse model that could be a promising model system for research into factors affecting mammalian embryonic development and disease.

NIH-Funded Scientists Develop Mouse Embryo Model That Generates Neural Tubes

ProBioGen will collobarate with NextPoint Therapeutics  to develop and manufacture its lead antibody candidate.

ProBioGen Executes Master Service Agreement with NextPoint Therapeutics

Meg Rivers is the former senior editor for 

Podcasts

In this episode of the Drug Solutions Podcast, John Koleng, VP of product development and manufacturing for TFF Pharmaceuticals shares outsourcing strategies in biopharma.

Drug Development

Research into Cold Cancers Heating Up

Development of Gamma-Delta T-Cell Therapies

QbD for Small-Molecule Continuous Process Development