Accurately targeted immunotherapies through reliable neoantigen recognition enable personalized medicine development.

Research into Cold Cancers Heating Up

Activation and expansion are essential for success in both autologous and allogeneic therapies.

Development of Gamma-Delta T-Cell Therapies

Continuous manufacturing and a quality-by-design development approach are a natural fit.

QbD for Small-Molecule Continuous Process Development

Topic

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Articles

Gernot Warnke, Head of R&D, JRS Pharma, spoke about excipients and how these relate to feeding in batch and continuous manufacturing. 

Equipment Trends in Advanced Solid-Dosage Drug Manufacturing: INTERPHEX Keynote Part 5

Feliza Mirasol is the science editor for 

Chris Spivey is director of Industry Relations and Strategic Partnership, MJH Life Sciences.

Part 2—Industry experts from MilliporeSigma, Lonza, Astrea Bioseparations, and Sartorius provide insight and examples about solving critical challenges in both analytics and process development for emerging therapies.

Advances in Molecule Characterization and Biomanufacturing for Emerging Therapies: Part 2

Pfizer’s investigational oral antiviral COVID-19 candidate reduced COVID-19-related hospitalization or death by 89% in patients who received it within three days of symptom onset.

Pfizer Pill Reduces Severe COVID-19 Risks by 89% in Phase II/III Study

Part 1—Industry experts from MilliporeSigma, Lonza, Astrea Bioseparations, and Sartorius discuss key issues affecting the development of emerging biotherapies.

Advances in Molecule Characterization and Biomanufacturing for Emerging Therapies: Part 1 

The agency found Lagevrio (molnupiravir) to be safe and effective at reducing the risk of death and hospitalization for those with mild to moderate COVID-19 infections.

MHRA Approves COVID-19 Antiviral Drug

Felicity Thomas is the former Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Investing in formulation strategies earlier on in development will maximize the chance of success.

The Earlier the Better for Formulation Strategies

The researchers will use 3D printing to design novel flow reactors and static mixers.

Almac Sciences Collaborates with Irish Manufacturing Research Organization on Flow Chemistry Reactors

Alternative drug delivery approaches are promising, but due to their complexity, they need to be sufficiently justified.

Taking an Alternative Approach to Drug Delivery

John A. Thomas is the president of M-Star Simulations.

Advances in simulation and the development of digital twins.

Computational Fluid Dynamics in Upstream Biopharma Manufacturing Processes

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

SEDDS and SMEDDS improve solubility and permeability while expanding efficacy and applicability.

Drug Development

Research into Cold Cancers Heating Up

Development of Gamma-Delta T-Cell Therapies

QbD for Small-Molecule Continuous Process Development