Manufacturing

Hallie Forcinio is packing editor for Pharmaceutical Technology and Pharmaceutical Technology Europe, editorhal@sbcglobal.net.

Articles

Container and equipment innovations expand applications.

Innovations Meet Growing Demand for Prefilled Syringes 

Amgen’s greenfield facility near Columbus, Ohio to assemble and package vials and syringes is expected to be operational by 2024. 

Amgen Builds Packaging Facility in Ohio

The new line can fill prefilled syringes, cartridges, and vials using ready-to-use components.

Aji Bio-Pharma to Add High Speed Fill/Finish Line to its San Diego Facility

Samsung Biologics plans to support the production of hundreds of millions of doses of Moderna’s vaccine to supply to markets outside of the United States beginning in the third quarter of 2021. 

Moderna and Samsung Biologics Partner on Fill/Finish Manufacturing of Moderna’s COVID-19 Vaccine

Felicity Thomas is Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Certain therapeutics, such as ophthalmics, must be provided as a sterile dosage form but can pose fill/finish challenges due to the small batch sizes required and the fact that the products used are difficult to fill and of high value.

Eyeing Up Success in Fill/Finish

BioNTech plans to expand its global footprint by establishing its regional headquarters for southeast Asia and a new mRNA manufacturing facility in Singapore. 

BioNTech to Establish Regional Headquarters and mRNA Manufacturing Facility in Singapore

Complex formulations, personalized medicines, COVID-19 therapies, and sustainability goals are driving innovations in drug packaging.

Injecting Innovation into Drug Packaging

Moderna’s investments will double the formulation fill/finish and drug substance manufacturing of its vaccine to up to three billion doses in 2022 at various manufacturing sites. 

Moderna Announces Additional Investments to Increase COVID-19 Vaccine Supply for 2022

Sanofi will perform the fill/finish of up to 200 million doses of Moderna’s COVID-19 vaccine at its Ridgefield, NJ, facility starting in September 2021. 

Sanofi to Manufacture up to 200 Million Doses of Moderna’s COVID-19 Vaccine

Under the terms of the expanded agreement, Catalent will provide Moderna with a new high-speed vial filling line until June 2023 along with inspection, labeling, cartoning, and final packaging for potential pipeline programs.

Fill-Finish