Development

Articles

PolySciTech's new launch, SpinSwiper, has the potential to speed up microparticle production.

PolySciTech's SpinSwiper Could Speed Up Production of Controlled-Release Microparticles

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Industry experts share their perspectives on key advances in controlled-release drug delivery and future innovations in this arena.

Advances in Controlled-Release Drug Delivery

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Lifecycle management opportunities are impacting the development of controlled-release technologies for solid-dosage drugs.

Controlled-Release Technologies Create Opportunities for Solid-Dosage Drug Formulators

Researchers at Massachusetts recently reported on the development of a drug-eluting contact lens designed to provide prolonged delivery of the glaucoma medication, latanoprost.

Contact Lens For Prolonged Delivery of Glaucoma Medication

Formulation and process considerations for ethyl cellulose aqueous dispersion in sustained-release applications.

Ethyl cellulose aqueous dispersion: a coating system for oral sustained-release dosage forms

GlaxoSmithKline recently developed a novel technology for the formulation of modified-release tablets. The authors describe the route from development to commercialization.

Development and Commercialization of a Novel Modified Release Tablet Technology

Gayatri C.Patel, M.Pharm, PhD, is associate professor in the Department of Pharmaceutics & Pharmaceutical Technology, Ramanbhai Patel College of Pharmacy at the Charotar University of Science and Technology, Changa Campus, Changa- 388 421, Anand, Gujarat, India, gayatripatel.ph@charusat.ac.in, +91 2697 265162.

Madhabhai M. Patel is a professor in the Department of Pharmaceutics, Kalol Pharmacy College, Kalol, Gujarat, India.

Chronotherapeutic drug delivery systems (CRDDS) have been recognized as potentially beneficial to the chronotherapy (timeoptimized therapy) of widespread chronic diseases that display time-dependent symptoms.

Developing a modified Pulsincap system

Generic-drug companies are increasingly viewing the development of controlled-release formulations as a way of obtaining a competitive edge, according to a report published by Espicom Business Intelligence in August 2009.

Controlled-release formulations targeted by generic companies

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

3M Drug Delivery Systems has successfully designed a proof of concept device using a solid microstructured transdermal system for the systemic delivery of high-potency pharmaceuticals. The technology was showcased at a poster session at the annual meeting of the Controlled Release Society held this week in New York City.

Solid Microstructured Transdermal Delivery Highlighted at Controlled Release Society's Meeting

Once considered mainly an afterthought in a company's lifecycle-management strategy, controlled-release dosage forms are now positioned at the forefront of many formulation strategies. In contrast to drug discovery, formulation work focuses not only on the intricacies of the active pharmaceutical ingredient (API), but also on fine-tuning the excipients, the release profile, and the delivery mechanism to provide optimal therapeutic benefit. Because of their wide range of applications and functionalities, especially in controlled-release therapies, polymers are among the most widely used excipients.

Formulation and Drug Delivery, Controlled Release