Development

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Articles

Virpax’s Patch-in-a-Can technology delivers pain medication using a metered-dose spray film.

Spray Film Provides Alternative to Patches

Drug and adhesive formulation are crucial to the development of microneedle patches for pharmaceutical transdermal delivery systems. 

Manufacturing Considerations for Transdermal Delivery Systems

Funding from Innovate UK will be used by Medherant to support manufacture of transdermal patches for clinical trials.

Medherant Receives Grant from Innovate UK for Transdermal Patch Manufacturing

Innovative technologies, such as drug-loaded devices and 3D printing, enable advances in implantable devices and other novel dosage forms.

New Dose Forms Focus on the Patient

Jon Lenn, PhD, is senior vice-president for MedPharm’s US operations. 

Marc Brown, PhD, is chief scientific officer and co-founder of MedPharm.

The human skin protects the body from physical, mechanical, and chemical insults while preventing endogenous water loss. This function is predominantly achieved by a thin (10–30 µm) cornified outermost layer-the stratum corneum (SC)-generated through terminal differentiation of the basal epidermal keratinocytes. The stratum corneum protects the human body, but also severely limits drug delivery into and across the skin.

A Perspective on the Topical Delivery of Macromolecules

Pharmaceutical companies are developing new strategies to address the ever-increasing development costs for new drug therapies and maximize the value of their existing drug portfolio.

Innovating Lifecycle Management with Data-Driven and Enabling Technologies

Mark Gordon is product manager at Trelleborg Sealing Solutions Healthcare and Medical

Andrew Gaillard is global director at Trelleborg Sealing Solutions Healthcare and Medical. 

API can be mixed with silicone and other polymers to create drug-delivery combination products. 

Designing Combination Products

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

With the right excipients, formulators can control when, where, and how an API is released.

Selecting Excipients for Controlled Release

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

The CUREfilm technology delivers drugs through a dissolvable strip that can be applied in the oral cavity or onto the skin. 

An Alternative to Pills and Injections: CUREfilm Redefines How Medicines are Delivered and Experienced

Choice of carrier can have a significant impact on the capsule filling process as well as the performance of the DPI formulation.

Formulation and Drug Delivery, Specialty Dosage Forms