Drug Development

Jeff Williamson is director of Product Development at Lonza.

Articles

API-in-capsule approaches enable pharmaceutical companies to quickly assess new drug candidates with reduced API consumption and to increase speed to clinic.

Application of API-in-Capsule Best Practices to Accelerate Drug Product Development

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Immobilizing the antibodies on a solid-phase support, such as a resin, and carrying out the conjugation of the payload-linker while the antibodies are bound to that support will prevent aggregation at its source.

Tackling Aggregation Challenges in ADC Production

Protagen Protein Services, a CRO, now offers quicker and more accurate characterization of biomolecular stability using differential scanning calorimetry (DSC).

Protagen Protein Services Expands Analytical Services for Biosimilar Development

The European Commission (EC) has approved Novartis’ chimeric antigen receptor T cell (CAR-T) cell therapy Kymriah for the treatment of B-cell acute lymphoblastic leukemia and relapsed or refractory diffuse large B-cell lymphoma after two or more lines of systemic therapy.

EC Approves Novartis’ Kymriah CAR-T Cell Therapy

Preliminary survey results rank the United States, Germany, and Japan as tier-one nations for bioprocessing performance and potential.

bioLIVE Survey Ranks Top Bioprocessing Nations

The Coalition for Epidemic Preparedness Innovations (CEPI) and vaccine manufacturer IDT Biologika will collaborate to develop and manufacture a vaccine against Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

CEPI, IDT Partner to Develop MERS Vaccine

Experts from the Partnership for Research on Ebola VACcination report on progress and uncertainties regarding a safe and effective Ebola vaccine.

Experts Reveal Ebola Vaccine Status and Potential

The National Institute of Allergy and Infectious Diseases began a first-in-human trial of an experimental live, attenuated Zika virus vaccine.

Zika Vaccine Clinical Trial Begins

The acquisition of Juniper expands and strengthens Catalent’s offerings in formulation development, bioavailability solutions, and clinical-scale oral dose manufacturing.

Catalent Acquires Juniper Pharmaceuticals

FDA approved the first generic version of EpiPen and EpiPen Jr (epinephrine) auto-injector.

Formulation and Drug Delivery