Drug Development

Articles

The agency has adopted guidelines on the pharmacovigilance of biological drugs.

EMA Adopts Biologics Pharmacovigilance Practices

Jacobs Engineering will provide engineering and construction services to expand the Novartis site in Huningue, France.

Novartis Expands Biologics Production in France

The GMP-certified facility will produce TruTag microtags for global pharmaceutical customers.

TruTag Technologies’ Manufacturing Plant Achieves GMP Compliance

Jill Wechsler is Pharmaceutical Technology's Washington Editor, jillwechsler7@gmail.com.

Zika vaccine development is hindered by technical challenges and funding shortfalls.

Funding for Zika Vaccine Hinders Development

Topical semi-solids, like creams, lotions and ointments are comprised of a complex mixture of microstructures or colloidal phases, frequently referred to as the Q3. These microstructures may include micelles, lamellar phases, polymer matrices, liquid crystalline and crystalline states of wax excipients, as well as the solid states of active pharmaceutical ingredients. Different topical medicated semi-solid formulations, spanning a range of treatment indications, reveal a variety of different microstructures.

Understanding the Role of Excipients in Topical Semi-Solid Microstructure and Critical Performance Parameters

Researchers at the ARC Centre of Excellence in Convergent Bio-Nano Science (CBNS) in Melbourne, Australia have developed a drug-delivery technology that circumvents first pas metabolism in the liver, thereby, enabling higher drug levels to reach the systemic circulation.

Exploiting Fat Absorption to Enhance Oral Bioavailability of Drugs

The Claristep filtration system from Sartorius improves preparation of samples for analytical testing.

Clarification System Enhances Reliable Sample Preparation

Catalent Pharma Solutions teamed with Zumutor Biologics to develop antibodies with enhanced ADCC activity.

Collaboration Develops More Efficacious Antibodies

Jacobs Engineering Group was awarded a contract to provide engineering services and procurement for Alnylam Pharmaceuticals’ new manufacturing facility in Norton, Massachusetts.

Alnylam Moves Forward on Multi-Product RNAi Facility

The design of Baxter BioPharma Solutions’ aseptic filling lines provides a case study in customizing containment systems for multi-product lines

Formulation and Drug Delivery