Drug Development

Articles

Phase I clinical trials of PfSPZ revealed it may protect healthy adults, who have not been exposed to Malaria before, for more than on year.

Investigational Malaria Vaccine May Protect Healthy Adults for More Than One Year

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

The production of antibody-drug conjugates requires biopharmaceutical and chemical manufacturing, and conjugation capabilities.

ADCs Challenge Manufacturers’ Skill Sets

MilliporeSigma expands its Carlsbad, California-based GMP capacity for viral and gene-therapy products by nearly 90%.

MilliporeSigma Expands California GMP Facility

Safe handling of HPAPIs requires determining exposure potential and selecting appro-priate containment strategies.

Choosing Containment Strategies For Highly Potent APIs

Randi Hernandez was science editor at Pharmaceutical Technology from September 2014 to May 2017.

Experts discuss some of the emerging trends in bioprocessing in 2016, including 4D bioprinting, 2D-NMR, and the CAR-T design space.

Visions for the Future of Biopharma Manufacturing

Bioprocess operations-from cell line selection to final filtration-can influence the consistency and purity of biologic drug substances.

Upstream and Downstream Operations Can Impact Biologic API Uniformity

Jim Greenwood is president and CEO of the Biotechnology Innovation Organization (BIO). He represented Pennsylvania’s 8thÂ district in the US House of Representatives from 1993 to 2005.

Policies for patient access to life-saving therapies must keep pace with biomedical innovation.

The Value of Saving Lives

Application for Sirdupla Uniformity of Delivered Dose Methodology

A QbD Method Development Approach for a Generic pMDI

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Armin Gerhardt, associate professor of Pharmaceutical Science, Concordia University Wisconsin School of Pharmacy, discusses the effects of moisture on product quality and how to achieve good control of moisture during pharmaceutical manufacturing operations.

Tackling Moisture Challenges in Solid Dosage Manufacturing

Michael Kuchenreuther, PhD, is a research analyst, at Numerof & Associates, Inc.

Immuno-oncology drugs are demonstrating patient benefits, but growing resistance to the high cost has implications for patients, market access, and manufacturers.

Formulation and Drug Delivery