Development

Felicity Thomas is Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Articles

Tight development timelines and accelerated approval pathways favor simple, cost-effective capsule formulations.

Capsule Innovations: Speeding Up Drug Development

is head of Solid Form Services at Lonza Pharma & Biotech and was previously 

principal scientist at Capsugel’s Bend, Oregon facility.

Innovative approaches to drug screening—such as evaluation to identify the optimal solid state of a molecule and in-vitro characterization to establish the optimal solid state of a molecule and the ideal bioavailability-enhancing technology—can help drug developers meet accelerated development timelines while managing risk.

Evaluating Drug Substance–Drug Product Interplay Accelerates Development

Esra’a Albarahmieh is associate professor, Pharmaceutical Chemical Engineering department of the School of Applied Medical Sciences, German Jordanian University.

Mohammad Khanfar is associate professor, Pharmaceutical Chemical Engineering department of the School of Applied Medical Sciences, German Jordanian University.

Emad Alzubi is instructor and workshop manager at the Industrial Engineering department of the School of Applied Technical Sciences, German Jordanian University.

This study suggests that using a simple centrifugal method can produce a natural polymer-blend molecule that can successfully be used as an oral delivery mechanism for poorly soluble drugs. 

Fabrication Modulation of Zein-based Fibers for Oral Delivery of Hydrochlorothiazide

Particle engineering is a useful tool to manipulate API particles into a form that is manufacturable and deliverable to the patient.

A Great Manipulation: The Value of Engineering Particle Properties

The European Commission has approved Lynparza (olaparib) for use in patients with germline BRCA-mutated (gBRCAm) metastatic pancreatic cancer within the European Union.

European Commission Approves Lynparza for BRCA-Mutated Metastatic Pancreatic Cancer

Lonza is making additional investments in its global particle engineering network for expanded capacity and specialized capabilities.

Lonza Announces Additional Investments in Global Particle Engineering Services

Demand for custom drug delivery solutions is increasing and bringing forth an exciting period of valuable, innovative development opportunities.

Demand for Custom Dosage Forms Fuels Innovation

Controlled-release formulations offer numerous advantages for developers and patients, and this market is expected to continue to experience growth in the near future.

Taking a Controlled Approach

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

The correct mix of excipients is crucial to the success of fast dissolving/orally disintegrating dosage forms.

Formulating for Convenience and Compliance

Increasing prevalence of drug misuse and abuse is driving a heightened and more stringent approach to abuse-deterrent formulations.

Formulation and Drug Delivery