Drug Development

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Articles

A surge in capacity in contract microbial and mammalian cell-culture is underway to meet rising production needs for biopharmaceuticals.

CMOs Expand Biologics Manufacturing

Catalysis plays a critical role in the synthesis of active pharmaceutical ingredients (APIs). It provides a way to improve yield, achieve desired stereoselectivity, improve reaction conditions, and synthesize increasingly complex APIs. Recent advances in catalyzed-olefin metathesis reveal its value and promise in the pharmaceutical industry.

What's Next In: Ingredients

In honor of Pharmaceutical Technology's 30th anniversary, the editors conducted a survey of 320 readers last spring to discuss industry advances and future directions. Here are some of your foward-looking responses.

Pharma Predictions

Michelle Hoffman, editorial director of Pharmaceutical Technology.

"May you live in interesting times," goes the allegedly ancient Chinese curse. Well, these have been "interesting times" indeed for those working in the pharmaceutical industry.

30 Years Hence: It Won't Be Your Parents' Pharmaceutical Industry

The permeation of drugs through the skin is compromised by the presence of polar functional groups such as thiols, alcohols, phenols, imides or amides. By transiently masking these polar functional groups as prodrugs the permeability of drugs containing these functional groups through the skin can be improved.

Enhancing Topical Delivery Using Prodrugs

A well-devised QPP, which has been agreed on and signed by both parties, saves time and makes it easier to complete activities such as design, installations and tests.

Practical guidelines for qualifying purified water systems

Lipid-based drug delivery systems - such as liposomes, micro-and nanoemulsions, self-emulsified drug delivery systems, and solid lipid micro-and nanoparticles - are becoming more popular because lipid materials are easily characterized, contain a high range of well-defined/tolerated surfactant molecules and can be developed for several administration routes.

Topical delivery of oily actives using solid lipid particles

Company and People Notes: ISP to raise prices, Patheon appoints CEO, more.

Company and People Notes: ISP to Raise Prices, Patheon Appoints CEO, More

GlaxoSmithKline agreed to acquire Reliant Pharmaceuticals for $1.65 billion in cash.

GlaxoSmithKline to Acquire Reliant Pharmaceuticals for $1.65 Billion

Company and People Notes: Cambridge Major Labs acquires ChemShop; Helix BioPharma restructures senior positions, more.