Drug Development

Articles

Company and People Notes: Novartis and MIT to study continuous processing, GSK appoints Andrew Witty as CEO, more.

Company and People Notes: Novartis and MIT to Study Continuous Processing, GSK Appoints Andrew Witty as CEO, More

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The European Fine Chemicals Group (EFCG) issued a position paper on excipients used in pharmaceutical manufacturing at CPhI Worldwide last week.

European Fine Chemicals Group Issues Position Paper on Excipients

Company and People Notes: Thermo Fisher Scientific buys Priority Solutions International, Wyeth elects new president and CEO, more.

Company and People Notes: Thermo Fisher Scientific Buys Priority Solutions International, Wyeth Elects New President and CEO, More

Identifying polymorphs is a crucial part of the drug-development process as researchers forward select methods to improve detection.

Advancing Approaches in Detecting Polymorphism

David R. Schoneker is chairman of the International Pharmaceutical Excipients Council of the Americas. He also is director of global regulatory affairs at Colorcon.

As China emerges as a significant supplier of pharmaceutical ingredients, it must assure other countries of the safety of its excipients.

Excipient Control Strategies in China

A roundup of news from exhibitors at CPhI Worldwide.

Exhibitor News

Ian C. Lennon, PhD, is a scientist and technology leader at Chirotech Technology Ltd.

Nicholas B. Johnson, PhD, is a business development and marketing manager at Chirotech Technology Ltd.

Paul H. Moran, PhD, is a research specialist at Chirotech Technology Ltd.

Single-enantiomer drugs represent an increasingly large share of new chemical entities, leading to approaches in asymmetric synthesis.

Manufacture of Asymmetric Hydrogenation Catalysts

Amidst debate, the European Pharmacopoeia Commission is working to include physical or "functionality-related characteristics" of exipient materials in its monographs.

Functionality-Related Characteristics of Excipients

Through consideration of the ionic equilibria of acids and bases, one may readily calculate the formation constant of a salt species solely on the basis of knowledge of the pKA value of the acid and the pKB value of the base.

Strategy for the Prediction and Selection of Drug Substance Salt Forms

Orally disintegrating tablets (ODTs) continue to attract attention as an alternative to conventional oral dosage forms.

Ingredients