Drug Development

Articles

A polymer excipient that reportedly reduces spray time has received its first registration in a finished drug product.

Germany paves the way for BASF

Poly(ethylene oxide) is gaining the attention of research and development organizations and its application is extending into a wide range of drug delivery systems.

Applications of Poly(ethylene in Drug Delivery Systems: Part II

Various systems and measures can be used to safely handle and process explosive pharmaceutical compounds in a range of manufacturing procedures.

Risk Management of the Explosive Dusts in the Pharmaceutical Industry: A Practical Approach

Bioadhesive films cast from aqueous blends of PMVE/MA have diverse uses, such as a means of establishing an electrically conducting interface for bioelectrodes and as an adhesive drug delivery matrix.

Excipient-Excipient Interactions in Pharmaceutical Systems Intended for Topical Application

New Excipient Guidance Doesn?t Fill Regulatory Gap

The authors propose a strategy for classifying and validating inprocess testing methods.

Analytical Methods Validation In-Process Control Methods for the Manufacture of Active Pharmaceutical Ingredients

The authors study the effects of sweet potato and cocoyam starches on the compressional and mechanical characteristics of a paracetamol tablet formulation using cornstarch BP.

Compression and Mechanical Properties of Tablet Formulations: Containing Corn, Sweet Potato, and Cocoyam Starches as Binders

Nanostructured lipid carriers are a new type of delivery system offering improved performance in terms of drug loading and long-term stability with the ability to form highly concentrated dispersions...

Nanostructured Lipid Carriers: A Novel Generation of Solid Lipid Drug Carriers

Lyn Hughes, PhD, is a global technical service manager for healthcare in the Process Solutions Groups at Rohm and Haas Company, Spring House Technical Center, 727 Norristown Road, Spring House, PA 19477-0904, tel. 215.641.7329, fax 215.619.1608, lhughes@rohmhaas.com

In this article, the author explains some of the technology behind using ion-exchange resins for drug delivery...

Ion Exchange Resinates — The Technology Behind the Mystery

This article examines the importance of core design and formulation on the quality of a film coated tablet...