Ingredients

The Development of a Floating Drug-Delivery System for Metronidazole

December 02, 2011

The authors developed a metronidazole-based floating drug-delivery system to investigate the effect of rate-controlling polymers on release pattern and duration of buoyancy in matrix tablets.

The Employment Outlook Brightens

December 02, 2011

Readers react to the economic turmoil of the past year and look longingly forward to 2012.

PQRI Case Study (8): Internal GMP Audit Program

December 02, 2011

The last in a series of eight case studies from the Product Quality Research Institute focuses on internal GMP audits.

PQRI Case Study (6): Packaging Line GMP Optimization

December 02, 2011

The sixth in a series of eight case studies from the Product Quality Research Institute focuses on packaging line GMP optimization.

Catalyzing the Synthesis

November 02, 2011

Researchers develop various catalytic approaches for improving yield, purity, stereoselectivity, and process conditions.

Near Infrared Analysis of Tablets Containing Two Active Ingredients

November 02, 2011

The study evaluates near-infrared analysis of tablets nominally containing 4 mg of chlorpheniramine maleate and 10 mg of phenylephrine hydrochloride per dose.

Water-Intrusion Test Integration

November 02, 2011

The authors describe the operational qualification of test accuracy with regard to temperature drift using a thermal-compensation algorithm on several freeze dryers.

PQRI Case Study (5): Nonsterile Facility Cleaning Requirements

November 02, 2011

The fifth in a series of eight case studies from the Product Quality Research Institute focuses on nonsterile facility cleaning requirements.

Pfizer Outlines Its Supply Strategy

October 02, 2011

John Kelly, vice-president of strategy and transitioning sites for Pfizer Global Supply, discusses the company's manufacturing and supply strategy and network.

Quality Issues for Multiregional Clinical-Trial Materials

October 02, 2011

The authors examine risk management relating to the quality issues of clinical-trial materials and discuss areas that would benefit from additional consideration and harmonization.