Development

Articles

A perspective from Pfizer on the lessons from small-molecule manufacturing that can be applied to biomanufacturing.

Manufacturing Perspectives: Lessons for Biomanufacturing from Small-Molecule Manufacturing

The author examines sample-preparations methods used in inductively coupled plasma–optimal emission spectroscopy for four test metals.

Sample Preparation for Quantitative Metal Impurity Testing

Achieving a consistent level of quality control could greatly reduce waste and save money for the pharmaceutical industry. But why has talk about Six Sigma died down at a time when it could be of great benefit?

Is Six Sigma Still Relevant for Drugmakers?

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The Society for Chemical Manufacturers & Affiliates commented on EPA's modifications to the Inventory Update Reporting rule, also broadly know as the Chemical Data Reporting rule. EPA issued the final rule earlier this month.

SOCMA Comments on EPA's Chemical Data Reporting Rule

Merck & Co. announced last week that it plans to reduce its global workforce, as measured by year-end 2009 levels, by an additional 12–13% by 2015. The company made the announcement as part of its second-quarter earnings release, which the company issued on July 29, 2011.

Merck Announces Further Restructuring, Job Cuts

Jane Wan is a freelance writer based in Singapore.

Contract manufacturing organizations throughout Asia are increasing their capabilities to meet market demand and attract foreign investment and partnerships.

Report from Asia

O-arylation and O-alkylation, a one-pot protein synthesis, a combined approach in continued and chemocatalysis, and green-chemistry applications are the target of some recent advances in API synthesis.

Improving API Synthesis

Eric Langer has over 25 years experience in biotechnology and life sciences strategic marketing management, market research, and publishing. He has held senior management and marketing positions at biopharmaceutical supply companies. He has published and authored many books and reports on topics in Biotechnology, Large-scale BioManufacturing, and bioscience commercialization and communication. He teaches at Johns Hopkins University marketing management, biotech marketing, services marketing, and marketing in a regulated environment. In 1989 he co-founded BioPlan Associates, Inc. to provide market analysis, and strategy to biotech and healthcare organizations.

China rises to the top as a destination for international outsourcing.

Offshoring Biomanufacturing

A path to personalized medicines creates a new paradigm for development and manufacturing.

Embarking on the New World of Personalized Medicine

The article examines a cross-functional supplier integration model to facilitate project management.

Ingredients