Development

Articles

The authors investigate the influence of hydro-alcoholic media on hydration and drug release from polyethylene oxide extended-release matrices.

The Influence of Hydro-Alcoholic Media on Drug Release

The current review describes the role and selection of excipients, pellet core, coating materials, and compression with various cushioning agents.

Multiunit Particulate Systems: A Current Drug-Delivery Technology

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

The IPEC Federation has issued a statement on the use of phthalates in pharmaceutical products in response to reports of adulteration of certain nutritional supplements, vitamins, foods, and beverages imported from Taiwan.

IPEC Federation Issues Statement of Phthalate Use

Merck and Hanwha Chemical have formed an exclusive global agreement to develop and a commercialize a biosimilar of Enbrel, a drug to treat moderate to severe plaque psoriasis, psoriatic arthritis, and moderate to severe rheumatoid arthritis.

Merck to Develop Biosimilar with Korean Chemical Manufacturer

Listen to roundtables from the 2011 ExcipientFest/IPEC conference, addressing developing issues in excipient functionality and continuous manufacturing.

Audio: Excipient Functionality and Continuous Manufacturing

The study results suggested that Pluronic F127 might be a potent inhibitor of drug precipitation for Labrasol formulations.

Inhibiting the Precipitation of Poorly Water-Soluble Drugs from Labrasol Formulations

India's drug pricing authority increased the retail costs of certain domestically manufactured drugs, but not those of imported drug products. Pharma is asking why.

Report from India

Effective containment in API and drug-product manufacturing encompasses a variety of process, equipment, and operational issues.

Optimizing High-Potency Manufacturing

Takeda Pharmaceutical has agreed to acquire Nycomed, a Swiss pharmaceutical company for $13.5 billion, excluding Nycomed's US dermatology business. The deal is intended to increase Takeda's presence in European and emerging markets.

Takeda to Acquire Nycomed

The Office of the United States Trade Representative issued a report as part of its annual review of the global state of intellectual-property rights protection and enforcement.

Ingredients