Drug Development

Articles

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Michelle Hoffman, editorial director of Pharmaceutical Technology.

Obama's cost-containment and science-innovation initiatives need to overlap.

Parallel Tracks

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

A review of recent product innovations, policy developments, and growth prospects in the excipients market.

Tracking Excipients

The financial and economic downturn is likey to have long-term implications for outsourcing.

Moving Toward a Drug Development Boon or Bust?

The authors demonstrate how melt-extrusion and spray-drying methods can help to prepare solid dispersions of poorly soluble drugs using Eudragit polymers.

Using Polymers to Enhance Solubility of Poorly Soluble Drugs

The authors examine common superdisintegrants (i.e., crospovidone Type A, crospovidone Type B, croscarmellose sodium, and sodium starch glycolate) with a set of poorly soluble drug actives and evaluate in vitro drug dissolution.

Influence of Superdisintegrants on the Rate of Drug Dissolution from Oral Solid Dosage Forms

The authors examine the use of a novel highly functional pregelatinized starch as a controlled-release matrix excipient.

A Novel Pregelatinized Starch as a Sustained-Release Matrix Excipient

The authors studied the behavior of anhydrous lactose and the combination of anhydrous lactose and the combination of anhydrous lactose with microcrystalline cellulose on a pilot-scale roller compactor.

Roller Compaction of Anhydrous Lactose and Blends of Anydrous Lactose with MCC

The authors examine the use of a hypromellose-based product as an excipient in a controlled release formulation using direct-compression tableting.

A New Hypromellose Excipient for Direct-Compression, Controlled-Release Applications

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Ingredients