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Articles

The authors examine common superdisintegrants (i.e., crospovidone Type A, crospovidone Type B, croscarmellose sodium, and sodium starch glycolate) with a set of poorly soluble drug actives and evaluate in vitro drug dissolution.

Influence of Superdisintegrants on the Rate of Drug Dissolution from Oral Solid Dosage Forms

The authors examine the use of a novel highly functional pregelatinized starch as a controlled-release matrix excipient.

A Novel Pregelatinized Starch as a Sustained-Release Matrix Excipient

The authors studied the behavior of anhydrous lactose and the combination of anhydrous lactose and the combination of anhydrous lactose with microcrystalline cellulose on a pilot-scale roller compactor.

Roller Compaction of Anhydrous Lactose and Blends of Anydrous Lactose with MCC

The authors examine the use of a hypromellose-based product as an excipient in a controlled release formulation using direct-compression tableting.

A New Hypromellose Excipient for Direct-Compression, Controlled-Release Applications

Also, Hospira to reduce workforce; WuXi AppTech makes senior appointments; more...

Company and People Notes: Daiichi Sankyo Sues 13 Generic Drugmakers; Ischemix Appoints CEO; More...

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

A bipartisan bill that would establish a regulatory pathway for the approval of biosimilars was introduced into the US House of Representatives last week.

Bipartisan Bill for Biosimiliars and Biogenerics Introduced in the House

The US Pharmacopeial Convention (USP) and the National Institute for the Control of Pharmaceutical Biological Products (NICPBP), China's agency for overseeing the quality of large- and small-molecule drugs, signed a memorandum of understanding (MOU) to bolster the quality of medicines in China and in the countries that buy Chinese drug products, including the United States.

USP and NICPBP Sign Memorandum of Understanding

Also, Genzyme receives warning letter; Mesa Laboratories appoints John J. Sullivan CEO and a member of the board of directors; more...

Company and People Notes: Gilead Sciences to Acquire CV Therapeutics; DOR Biopharma Appoints Chief Medical Officer; More...

Also, Penn Pharma to expand; stem cell research funding ban lifted; Bristol-Myers Squibb made senior appointments; more...

Company and People Notes: MannKind to Purchase Pfizer Facility; Catalent Appoints President and CEO; More...

The Synthetic Organic Chemical Manufacturers Association (SOCMA) said last week that Congress is likely to the include inherently safe technology (IST) measures in proposed chemical site-security legislation that is likely to be introduced in late winter or early spring.

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