Drug Development

Articles

The European Pharmacopoeia Commission adopted revised monographs for heparin calcium and heparin sodium to strengthen the level of testing required for quality control.

European Pharmacopeia Adopts Revised Heparin Monographs

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

A recent US government study shows that follow-on biologics are likely to have a favorable economic impact if proposed legislation authorizing a regulatory pathway in the US is approved.

The Economics of Follow-on Biologics

Also, Covance and WuXi PharmaTech to form contract research joint venture in China, Covidien makes appointments to its Pharmaceutical Products and Imaging Solutions businesses, more...

Company and People Notes: Schering-Plough and Merck Withdraw NDA and Terminate Respiratory Joint Venture, Cell Biosciences Names Management Team, More...

Richard E. Maleczka Jr. and Milton R. Smith III, professors of the Department of Chemistry at Michigan State University, were recognized by the Environmental Protection Agency's Presidential Green Chemistry Challenge Awards, for designing a catalytic reaction to synthesize precursors for the Suzuki-coupling reaction.

Green Route for Precursors for Suzuki Coupling Recognized

Molecular Profiles created a poster that demonstrates the efficacy of its "nanoPASS" (nanoscale predictive analytical screening solution) technique to characterize an active pharmaceutical ingredient's (API) surface energy.

Nanoscale Technique Measures Surface Physical Properties of APIs

Michelle Hoffman, editorial director of Pharmaceutical Technology.

With no economic relief in sight, industry, like all of us, is grappling with high-and new-costs.

How to Pay for it All?

The year 2007 was slow for approvals for new molecular entities and overall pharmaceutical industry growth. Big Pharma seeks relief in a growing biologics portfolio.

Charting API Market Growth and Opportunity

Paul Kippax is product manager at Malvern Instruments.

Nasal drug delivery depends on many factors, including the conditions of use by the patient, the drug formulation, and the spray pump and aerosol characteristics. In recent years, the types of drug administered via the nasal route have expanded from locally acting drugs, such as those for allergic rhinitis, to delicate molecules for systemic activity, such as vaccines, proteins and peptides, which can be difficult to administer noninvasively. While the nasal cavity provides a delivery pathway for these large molecules, the rate of mucociliary clearance in the nasal cavity may hinder the extent of absorption. Therefore, formulators must develop mechanisms that improve absorption for high molecular weight compounds.

Enhancing the in vitro assessment of nasal sprays

The US Pharmacopeia (USP) posted revised monographs for heparin sodium and heparin calcium on its website.

USP Posts Revised Heparin Monographs

Also, Stiefel Laboratories will acquire Barrier Therapeutics, Danube Pharmaceuticals appoints Brian Levy COO, more...

Ingredients