Manufacturing

Articles

The therapy, indicated for a rare form of B-cell non-Hodgkin’s lymphoma, was developed by Kite, a Gilead company, which will manufacture the therapy at its facility in El Segundo, CA.

FDA Approves First Cell-Based Gene Therapy for MCL

Feliza Mirasol is the science editor for 

The early success seen on the market for approved cell and gene therapies poses both technical and manufacturing challenges for pipeline candidates on the road to commercialization.

Commercialization Poses Challenges for Cell and Gene Therapies

Sangamo will receive a $75 million upfront license fee payment and will be eligible to earn up to $720 million in other development and commercial milestone payments, including up to $420 million in development milestones and up to $300 million in commercial milestones. 

Novartis and Sangamo Announce Gene Therapy Collaboration for up to $795 Million

This method is expected to help bring gene therapies to market faster, safer, and cheaper.

A Novel Method for Host Cell Protein Analysis

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

RNA is easier to manipulate than DNA but challenging to deliver to the right cells.

Can RNA Simplify Gene Therapy Development?

The site can now support customized product and bioprocess development and custom cell and gene therapy reagent manufacturing. 

Avantor Expands its New Jersey Innovation Center

The companies are entering into a license agreement to provide CSL Behring with exclusive global rights to etranacogene dezaparvovec, uniQure’s investigational gene therapy for patients with hemophilia B. 

uniQure, CSL Behring Collaborate on Hemophilia B Gene Therapy in Over $1.6-Billion Deal

The company will invest $75 million into its Canton, MA, facility to expand its viral vector, gene therapy, and contract development and manufacturing capabilities.

Emergent to Invest $75 Million to Expand Manufacturing Capabilities

Agnes Shanley is senior editor of Pharmaceutical Technology.

Previous investments set a foundation for later efficiency improvements. 

2019 Investments Centered around Cell and Gene Therapies

The VIA Capsule from Cytiva is a liquid nitrogen-free cryogenic shipment system designed to transport cell therapies.

Manufacturing, Gene Therapies