Manufacturing

Agnes Shanley is senior editor of Pharmaceutical Technology.

Articles

ASTM’s E-55.05 committee aims to turn best practices into industry standards in order to eliminate variability and allow a 70-year-old process to leverage 21st century tools, technologies, and practices.

Can Standards Help Pharma Modernize Lyophilization?

Ed Trappler is president and founder of Lyophilization Technology, Inc. a contract research and technical services firm dedicated to freeze drying. He has over 40 years of experience in lyophilization that ranges from product development to equipment application engineering. He received his Bachelor of Science degree in chemistry at The College of New Jersey. His experience in the pharmaceutical industry includes product development, toxicology supply preparation, clinical manufacturing and parenteral production.

Amy M. Bosch is Scientist I at Lyophilization Technology, Inc. (LTI). As a Scientist I and Project Director, she is involved in managing client projects including product and process development, clinical and toxicological material preparation, technical support, and troubleshooting. Amy holds a B.S. degree from Millersville University in Biology. 

Understanding the advantages and suitability of different methods to measure residual moisture content in lyophilized materials--and the respective limitations--aids in selecting the most appropriate method for testing.

Residual Moisture Testing Methods for Lyophilized Drug Products

Telstar has a dedicated process analytical technology (PAT) corner at its booth to display new developments for pharmaceutical freeze drying systems and aseptic manufacturing processes. 

Telstar Presents PAT Tools for Freeze Drying and Aseptic Manufacturing at Achema 2018

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Determining the right process conditions for a freeze-drying cycle requires an understanding of the effect of each step on the drug product.

Freeze-Drying Process Optimization

Researchers at Purdue University and and industry experts have partnered up at the Advanced Lyophilization Technology Hub to optimize the 70-year-old freeze-drying process. 

Experts Partner to Optimize Lyophilization

Agnes Shanley is senior editor of BioPharm International.

A technology roadmap aims to drive and consolidate improvements in a process that has remained unchanged for more than 70 years.

Modernizing Lyophilization

Focused around Purdue University’s LyoHUB, a new blueprint aims to bring innovation to equipment and processes. One goal? Continuous freeze drying.


Experts Set a 10-Year Roadmap for Optimizing Lyophilization

Dalton Pharma Services completed an expansion in sterile filling and API manufacturing at its cGMP facility in Toronto, Canada.

Dalton Expands Canadian Manufacturing Facility

Recipharm is investing EUR3.7 million (approximately $4.18 million) to increase lyophilization capacity at its Masate facility in Italy.

Recipharm Expands Lyophilization Capacity in Italy

The company manufactures biological drug products and intermediates for the allergy vaccine market.

Manufacturing, Lyophilization