Manufacturing, Solid Dosage Drugs

Mitigating Risk in Formulating with Excipients

April 01, 2020

Tools help improve understanding of excipient risk in formulating OSD drugs.

Quantitative Rupture Testing of Soft Gelatin Capsules: Understanding Aberrant Results

February 02, 2020

This paper discusses what causes cross-linking, how cross-linking is addressed with addition of enzymes, and consideration for occasional high results that can be obtained during release testing.

Self-Guided Control of a Fluid Bed Granulation Process

January 02, 2020

Advanced dynamic process control of a fluid-bed granulation process using PAT data improves product quality.

Study Demonstrates Digitalization of Tablets

December 21, 2019

A coalition establishes a secure, direct link between a physical tablet and a digital backend for supply chain integrity.

E-Learning Helps Boost Production Efficiency

October 22, 2019

Improving operator skills using flexible, online training benefits pharmaceutical tableting operations.

UK Collaboration Uses a Direct Compression Digital Twin to Speed OSD Formulation

October 10, 2019

CPI, the University of Strathclyde, GSK, and AstraZeneca Collaborate on a continuous direct compression digital twin for pharmaceutical formulation optimization.

Best Practices in Handling HPAPIs

October 02, 2019

Establishing OEL data and ensuring appropriate engineering controls are crucial aspects of safe handling.

The Road to Real-Time Release: At-line NIR Testing

September 02, 2019

At-line NIR measurements can replace a laboratory HPLC measurement for API content in oral solid-dosage drug manufacturing.

Putting NIR to Good Use in Tablet Formulation and Manufacture

September 02, 2019

In this interview, the main uses and benefits of NIR spectroscopy in tableting are discussed.

Industry Experiences in Continuous Manufacturing for Encapsulation and Tableting

September 02, 2019

Early adopters of continuous manufacturing approaches shared their plans and some of their experiences at the 11th annual Charles Jarowski Symposium in Industrial Pharmacy.