Manufacturing

Fernando J. Muzzio, PhD, is a professor and the director of the pharmaceutical engineering program at the Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854-8058, tel. 732.445.3357.

Engineering Research Center for Structured Organic Particulate Systems (ERC-SOPS), Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

M. Sebastian Escotet-Espinoza is a graduate research assistant at the Chemical and Biochemical Engineering Department at Rutgers, The State University of New Jersey,

Sharmista Chatterjee is acting branch I chief/division 1 of process assessment/Office of Process and Facilities, at the Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA.

Thomas O’Connor is chemical engineer, science staff at the Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA.

Sau Lee is acting associate director for science at the Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA.

Maitraye Sen is a graduate research assistant at the Chemical and Biochemical Engineering Department at Rutgers, The State University of New Jersey.

Articles

In-silico design facilitates process optimization and evaluation of process control strategies.

Flowsheet Models Modernize Pharmaceutical Manufacturing Design and Risk Assessment

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Multivariate data analysis (MVDA) is being used to effectively handle complex datasets generated by process analytical technology (PAT) in biopharmaceutical process development and manufacturing.

Multivariate Data Analysis Finds Use In Biopharmaceutical Process Development And Scale-Up

Use of modeling software can help improve process understanding, and can be used in open- or closed-loop control.

How Modeling Software Can Help Process Development

Real-time, noncontact imaging and spectroscopy techniques provide insight into pharmaceutical processes.

Advances in Process Analytical Technology Improve Understanding

The new flow sensors, BioPAT Flow, enable precise, reproducible data to be collected on flow rates and mass balances without coming in contact with the medium during measurement.

Sartorius Stedim Biotech Forms Pact with em-tec to Develop PAT Solutions for Flow Rate Measurements

PAT has aided formulation, both pre-and post-filing, by reducing costs and time frames.

Simplify Formulation With PAT

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Innovative Excipients in Solid-Dosage Manufacturing

A new release of FactoryTalk Batch software from Rockwell Automation eases recipe creation and adds security.

Process Automation Software Eases Recipe Creation

Siegfried Schmitt, PhD, is Vice President Technical at Parexel International, Siegfried.Schmitt@parexel.com.

Siegfried Schmitt, Principal Consultant, PAREXEL International, discusses the benefits of automated processes.

Automation: A Cure-All?

Pharmaceutical Technology’s survey collected industry feedback on trends and the utility of equipment used in finished drug-product manufacturing.

Process and Automation