Drug Development

Agnes Shanley is senior editor of Pharmaceutical Technology.

Articles

Continuous manufacturing may offer huge opportunities, but it will not be right for
every facility or product.


Batch or Continuous? Ask the Right Questions During Scale Up

More manufacturers are embracing MAM, which simplifies biopharmaceutical product quality testing, and facilitates the measurement and monitoring of critical quality attributes.

Using the Multiple Attribute Method for Process Development and Quality Control

While the multiple attributes method gains ground and traditional lab methods improve, broad efforts are underway to determine biopharmaceuticals’ most significant critical quality attributes and enable real-time release.

Getting a Handle on Biopharm’s Most Critical Quality Attributes

Large biopharmas, emerging biotechs, and CMOs are looking for novel ways to improve the productivity of biologics in a rapidly evolving biotherapeutics market.

The Search for Bioprocess Productivity Improvement

The UK’s Centre for Process Innovation is collaborating with partners GSK and AstraZeneca to establish a continuous wet granulation manufacturing facility for small-scale development of oral solid-dosage pharmaceuticals.

CPI Builds Open Innovation Facility for Continuous Wet Granulation

Merck KGaA opened a collaborative bio/pharma development facility in Molsheim, France and announced an investment plan through 2025 for its Darmstadt, Germany headquarters.

Merck KGaA Opens Development Center in France and Invests in Darmstadt Headquarters

The companies aim to assess automated CAR-T cell therapy manufacturing at the point-of-care and develop technologies to facilitate patient access to immunotherapies.

Lonza, Sheba to Collaborate on Automated Cell-Therapy Manufacturing

Joshua Zhang is head of WuXi STA’s Jinshan site.

Process optimization improves process mass intensity, reduces environmental impact, and improves cycle time for bio/pharmaceutical processes.

Improving Process Mass Intensity for Bio/Pharmaceutical Production

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

New technologies in the digital factory enhance quality, efficiency, and flexibility for bio/pharmaceutical manufacturing.

Embracing the Digital Factory for Bio/Pharma Manufacturing

Teva will apply Insilico’s technology for predictive biomanufacturing to create more efficient biomanufacturing processes.

Process and Scaling