Development

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Articles

Numerous benefits will eventually lead to large-scale applications in pharmaceutical manufacturing. 

Electrochemistry for API Synthesis

NRG Therapeutics and Domainex aim to develop novel small-molecule drugs to treat neurodegenerative disorders, such as Parkinson’s disease.

NRG Therapeutics and Domainex Partner on Parkinson’s Disease Drug Development Project

Lack of toxicity data and poor physicochemical properties must be overcome.

Challenges to Formulation Development for Highly Potent APIs

Evonik has launched new EUDRATEC technology to improve solubility and performance of oral small molecules. 

Evonik Launches New EUDRATEC Technology to Improve Solubility of Oral Small Molecules

Piramal Pharma Solutions plans to construct a multipurpose ADC manufacturing and aseptic fill/finish facility in Grangemouth, Scotland, and to upgrades its existing API manufacturing facility in Morpeth, England.

Piramal Pharma Solutions Expands and Upgrades UK Manufacturing Facilities

Meg Rivers is the former senior editor for 

Chris Spivey is director of Industry Relations and Strategic Partnership, MJH Life Sciences.

Videos

In this episode of Drug Digest, Chris Spivey, editorial director, and Meg Rivers, senior editor, dive into APIs, excipients, and formulation advances, specifically pairing the right APIs and excipients for optimizing formulations.

Drug Digest: Pairing the Right APIs and Excipients for Optimizing Formulations

Podcasts

In this episode of the Drug Solutions podcast, Chris Spivey, editorial director, and Meg Rivers, senior editor, interview experts on up-and-coming 2022 trends in the bio/pharma industry.

Drug Solutions Podcast: 2022 Bio/pharma Trends: US-Based Suppliers, Digitization, and Sustainability

Navigating a complex global regulatory landscape involves upfront research into the expectations of the different regulatory bodies, thorough documentation of every step of the API manufacturing process, and good communication. 

Global Regulatory Approach to API Manufacturing

Between dosage form versatility, product stability, lack of storage restrictions or need to refrigerate, and an easier means of purification, small-molecule APIs present an appealing market niche.

API Development and Manufacturing: Advantages of Working with Small Molecules

Drug makers are going beyond continuous improvement and green chemistry to increase the sustainability of small-molecule manufacturing.

Small-Molecule APIs