Dosage Forms

Fernando J. Muzzio, PhD, is a professor and the director of the pharmaceutical engineering program at the Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854-8058, tel. 732.445.3357.

Engineering Research Center for Structured Organic Particulate Systems (ERC-SOPS), Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

M. Sebastian Escotet-Espinoza is a graduate research assistant at the Chemical and Biochemical Engineering Department at Rutgers, The State University of New Jersey,

Sharmista Chatterjee is acting branch I chief/division 1 of process assessment/Office of Process and Facilities, at the Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA.

Thomas O’Connor is chemical engineer, science staff at the Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA.

Sau Lee is acting associate director for science at the Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, FDA.

Maitraye Sen is a graduate research assistant at the Chemical and Biochemical Engineering Department at Rutgers, The State University of New Jersey.

Articles

In-silico design facilitates process optimization and evaluation of process control strategies.

Flowsheet Models Modernize Pharmaceutical Manufacturing Design and Risk Assessment

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

A drug-product manufacturing classification system (MCS) for oral solid-dosage forms is proposed by an Academy of Pharmaceutical Sciences working group.

Choosing oral solid-dosage production processes: Could a classification system help?

Penn Pharma's equipment addition meets growing need for continuous dry granulation and for handling of highly potent drugs.

Penn Pharma Adds Contained Roller Compaction Equipment in South Wales

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Innovative equipment, analytical techniques, software, and modeling systems are improving the tableting process.

Advances in Tableting

Vilayat A. Sayeed is Director, Division of Chemistry III.

Taste may be subjective, but it is crucial to patient compliance, particularly for pediatric treatments.

Assessing and Improving the Palatability of Pharmaceuticals

Paul Kippax is a product manager, Laser Diffraction, Malvern Instruments Ltd., Enigma Business Park, Grovewood Road, Malvern Worcestershire, UK WR14 1XZ, Paul.Kippax@malvern.co.uk.

Analytical technologies must accurately identify and measure the critical material attributes of APIs and excipients.

Analytical Techniques for Oral Solid Dosage Formulation

PAT has aided formulation, both pre-and post-filing, by reducing costs and time frames.

Simplify Formulation With PAT

Agnes Shanley is senior editor of Pharmaceutical Technology.

Ionic liquid technologies offer a new way to improve bioavailability.

Boosting Solubility in Lipid-Based Formulations

New cellulosic polymers have been shown to improve solubility in these key amorphous solid dispersion processes.

Using Polymers for More Efficient Hot-Melt Extrusion and Spray Drying

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

While the skin offers an alternative route of administration for local and systemic drug delivery, developing semi-solid dosage forms can be a challenge.

Solid/Semi-Solid Dosage