Dosage Forms

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Articles

The correct mix of excipients is crucial to the success of fast dissolving/orally disintegrating dosage forms.

Formulating for Convenience and Compliance

Gerry P. McNally is principal of McNally Consulting Group, LLC. With more than 25 years of experience, he earned a BS and PhD in chemistry from University College, Dublin, Ireland and holds more than 25 patents in drug delivery and formulation. He can be reached at gmcnally47@aol.com.

A quick look at the history of OTC dosage form development shows the importance of patient-centered innovation.


Oral Dosage Form Innovation in OTC Pharmaceuticals

Matt Bundenthal is direct sales and communications manager at Fette Compacting America, www.fetteamerica.com .

Risk levels should be considered when designing containment for pharmaceutical tableting equipment to enhance operator safety.

Understanding Containment for Tableting

Felicity Thomas is the former Associate Editorial Director of Pharmaceutical Technology, Pharmaceutical Technology Europe, BioPharm International.

Understanding formulation properties early in development can prevent some costly issues later on.


A Little Thought Goes a Long Way in Tableting

OSD forms are popular within the industry due to the various advantages they offer, but there are specific considerations required to get the best OSD form possible.


In Top Tablet Form

This article examines multi-tip tool technology for pharmaceutical tablet compression and the process control and validation issues that must be carefully evaluated to assess the potential for success. 

Considerations for Tablet Compression with Multi-Tip Tooling

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Tools help improve understanding of excipient risk in formulating OSD drugs.

Mitigating Risk in Formulating with Excipients

Understanding European GMPs and new rules from China for excipients are crucial for formulating solid-dosage drugs. 

Considering Excipient Regulations

Tim Roach is senior director of plant engineering at Recro Gainesville.

Careful design, planning, and record keeping are needed for cleaning and changeover in multiproduct pharmaceutical facilities.

Best Practices for Design and Operation of Multiproduct Manufacturing Facilities

Chris O’Callaghan is senior product manager at Innopharma Technology, Dublin, Ireland, ocallaghanc@innopharmalabs.com.

Ian Jones, PhD, is founder and CEO of Innopharma Technology and Innopharma College of Applied Sciences, Dublin

Caroline McCormack  is process laboratory manager at Innopharma Technology, Dublin, Ireland.

Luke Kiernan is a PhD student at the Technological University Dublin in Ireland.

Gavin Walker, PhD, is professor and director of the Synthesis and Solid State Pharmaceutical Centre at the University of Limerick in Ireland.

Gareth Clarke is Multieye Product Manager, Innopharma Technology, Dublin,Ireland

Advanced dynamic process control of a fluid-bed granulation process using PAT data improves product quality.

Solid/Semi-Solid Dosage