Dosage Forms

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Articles

Experts from Colorcon share insights on how manufacturers can play a role in minimizing the risk of medication errors by ensuring that the medicines they develop are well differentiated, especially between dosages of the same product.


Reducing Medication Errors

Pharmaceutical companies are increasingly adopting patient-centric formulation development to ensure that drug products adequately meet the needs of end-users in all target patient populations.


Patient Centricity Takes Center Stage

David Vodak, PhD, is senior director at Capsugel’s Bend, Oregon facility.

is head of Solid Form Services at Lonza Pharma & Biotech and was previously 

principal scientist at Capsugel’s Bend, Oregon facility.

Model-based formulation and technology selection methodologies facilitate rapid product development.


Selecting the Appropriate Technology for Oral Bioavailability Enhancement

Eli Lilly was awarded the 2017 FOYA Overall Winner for its continuous direct compression manufacturing installation projects.

Eli Lilly Wins 2017 Facility of the Year Award

The company has passed inspection by the UK Medicines and Healthcare products Regulatory Agency, and is now licensed to develop, manufacture, and pack non-potent and potent solid oral drug products at its site in Loughborough, England.

Almac Group’s UK Manufacturing Facilities Pass MHRA Inspection

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Support from FDA, a best practice guide, collaborative research, and new facilities signify progress in solid-dosage continuous manufacturing.  

Continuous Manufacturing Presses On

Continuous twin-screw granulation offers several options for increasing production scale. Thermo Fisher Scientific explains factors to consider in scale-up projects for manufacturing oral solid-dosage drugs. 

Scaling Up a Continuous Granulation Process

Ad Gerich is managing director, InProcess-LSP, The Netherlands

Michiel Damen is application specialist, InProcess-LSP, The Netherlands.

Willy Verhoeven is senior scientist, Polymeric Dosage Forms, MSD Oss, The Netherlands.

Sai Prasanth Chamarthy is associate director, Respiratory Product Development, Merck & Co, Rahway, NJ USA.

Rut Besseling is director, Science and Technology, InProcess-LSP, The Netherlands.

This study shows that the presence of API lumps can be detected by inline NIR, and elaborates on why NIR sensor dimensions and actual measured sample volume by the NIR sensor are important variables for adequate interpretation of obtained results.

Detection of Lumps in Powder Blends by Inline NIR

Carolina Diaz Quijano, PhD, is manager of Innovation and Technical Marketing Nutra/Pharma at Omya International AG, Baslerstrasse 42, 4665 Oftringen, Switzerland, info.pharma@omya.com.

Functionalized calcium carbonate provides high porosity, which enables fast disintegration, and excellent compactibility that results in harder tablets at low compression forces. 

A Multifunctional Mineral Excipient

Agnes Shanley is senior editor of Pharmaceutical Technology.

Eric Jayjock, Patheon’s director of continuous manufacturing, discusses the CDMO’s plans for its new continuous manufacturing business. 

Solid/Semi-Solid Dosage