Dosage Forms

Articles

Bosch’s Xelum platform is designed for continuous production of oral solid-dosage forms.

Bosch Introduces Continuous OSD Manufacturing Platform

Matt Bundenthal is direct sales and communications manager at Fette Compacting America, www.fetteamerica.com .

Learn how to prevent common causes of product loss.

Optimizing Yields on Modern Tablet Presses

Jennifer Markarian is manufacturing reporter for Pharmaceutical Technology.

Although technical paths for continuous solid-dosage manufacturing have been laid out and equipment and control systems have been developed, industry is slow to move forward.

Paving the Way for Continuous Manufacturing

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

Design of experiment plays a crucial role in the optimization process of formulation development.

Designing Optimized Formulations

Anil Kane, executive director, Global Head of Formulation Sciences, Pharmaceutical Development Services at Patheon discusses key parameters in the development and manufacturing of oral solid-dosage forms.

Key parameters to be optimized in the development and manufacturing of oral solid-dosage forms

Christian Dunne is Aseptic global product manager at ChargePoint.

A chlorine dioxide sterilization cycle was developed for a novel split-valve aseptic powder transfer device.

Preventing Contamination During Sterile Powder Transfer

Agnes Shanley is senior editor of Pharmaceutical Technology.

A venture between GEA and Siemens aims to familiarize more pharmaceutical companies with more modern control and continuous processing.

Making PAT and Continuous Manufacturing Accessible

Johannes G. Khinast is professor at the Institute of Process and Particle Engineering, Graz University of Technology, Austria

Josef Lingitz is project manager, M&R Automation GmbH, Graz, Austria.

Sharareh Salar-Behzadi is principal scientist atResearch Center Pharmaceutical Engineering (RCPE)GmbH, Graz, Austria.

Stephan Sacher is senior scientist at the Research Center for Pharmaceutical Engineering GmbH in Graz, Austria.

This novel technology was developed in response to challenges involved in conventional manufacturing of multilayer tablets, including in-line control of the tablet weight, the tendency to delamination, direct contact between the two tablet layers, and cross contamination.

Gluing Pills Technology for the Production of Multi-Layer Tablets

Lawrence H. Block, PhD, is a professor of pharmaceutics at the School of Pharmacy, Duquesne University, Pittsburgh, PA 15282, tel. 412.396.6362, fax 412.396.5599, block@duq.edu.

Catherine Sheehan is the director for the excipients group at the United States Pharmacopeia in Rockville, Maryland.

This article summarizes the evolution of the viscosity standards and their corresponding applications in the USP−NF compendia.

Characterization of Polymeric Excipients

Smruti P. Chaudhari, PhD, is a development scientist at Metrics Contract Services.

A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation.

Solid/Semi-Solid Dosage