Dosage Forms

Articles

FDA and BARDA awarded a contract to Continuus Pharmaceuticals to develop an end-to-end continuous manufacturing process for solid-dosage drugs.

Continuus Pharmaceuticals Partners with FDA and BARDA

Martin KÃ¶berle, PhD, is head of Analytical Development &Stability Testing, at Hermes Pharma.

Detlev Haack, PhD, is head of Research & Development at Hermes Pharma.

Hot-melt coating was used to develop taste-masked orally disintegrating granules of acetaminophen and caffeine.

From Bitter to Sweet: Developing a User-Friendly Painkiller

Catalent adds two softgel facilities and packaging capabilities with acquisition of Canada-based Accucaps.

Catalent Expands Softgel Capacity with Accucaps Acquisition

Elizabeth Rivera is a technical services manager at the Life Sciences Division of STERIS Corporation.

Paul Lopolito is a technical services specialist at STERIS, Mentor, OH.

A lifecycle approach can be used to develop GMP-compliant cleaning procedures for continuous manufacturing of solid-dosage pharmaceuticals.

Cleaning Validation in Continuous Manufacturing

Fernando J. Muzzio, PhD, is a professor and the director of the pharmaceutical engineering program at the Department of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854-8058, tel. 732.445.3357.

C-SOPS, Department of Chemical and Biochemical Engineering at Rutgers, The State University of New Jersey

Shear-sensitive ingredients in a tableting formulation experience different conditions in a batch tumble blender than they would in a continuous paddle blender.

Lubrication in Continuous Tubular Powder Blenders

Adeline Siew is editor for Pharmaceutical Technology Europe. She is also science editor for Pharmaceutical Technology.

A dissolution method should have adequate discriminatory power to detect formulation changes that affect the dissolution rate of a drug product.

Dissolution Testing

Sharon Nowak is Global Business Development Manager for the food and pharmaceutical industries, K-Tron (Schweiz) AG.

Designing loss-in-weight feeders for accurate and consistent refill is crucial to a continuous solid-dosage process.

Improving Feeder Performance in Continuous Pharmaceutical Operations

Excipients play a crucial role in the manufacturing of solid-dosage forms and the performance of the finished drug product.

Excipients for Formulation Success

Three-dimensional (3D) printing, which is a type of additive manufacturing (AM), enables fabrication of specialty drugs and medical devices, said Emil Ciurczak, Doramaxx Consulting and CPhI expert panel member, in the 2016 CPhI Annual Industry Report.

A Vision for 3D Printing in Pharma Manufacturing

Ajay Pazhayattil*, M.Pharm, DBA, Ajay.Pazhayattil@capcium.com, is vice-president, Scientific and Regulatory Affairs at Capcium.

Flexible batch sizes for semi-continuous unit operations, such as tableting and encapsulation, can improve efficiency while maintaining quality.

Solid/Semi-Solid Dosage