Coated Plungers for Large Volume Biologics

Published on: 
Pharmaceutical Technology, Pharmaceutical Technology, December 2024, Volume 48, Issue 12
Pages: 8

Datwyler has launched new coated plungers in its NeoFlex line that are suitable for large volume biologics.

Datwyler’s newly launched coated plungers in the NeoFlex line come in sizes fit for containers aimed at large-volume auto-injectors and wearable devices. The new prefilled syringe 10 mL with its NeoFlex Cartridge Wearable 10 mL is designed for high quality and safety standards with the new plungers, which ensure the stability and safety of large-molecule drugs. These plungers are completely covered in a non-fluorosurfactant grade fluoropolymer coating, which prevents rubber particles from shedding and minimizes degradation from extractables and leachables. The plungers are inherently lubricious, which eliminates the need for silicone to ensure smooth operation inside the syringe or cartridge barrels. This characteristic also supports compatibility with complex formulations, which is especially crucial for the effective delivery of a highly sensitive, highly viscous biologic.

Datwyler