Innovations in Pregastric Absorption Drug Delivery and Orally Disintegrating Tablets

Join this webinar to explore the latest innovations in pregastric absorption. Learn more about advancements in buccal and sublingual delivery systems, the impact of permeation enhancers, and the role of physiologically based pharmacokinetic (PBPK) modeling in predictive formulation design.

Register Free: https://www.pharmtech.com/pt_w/pregastric-absorption

Event Overview:

In today's competitive pharmaceutical landscape, drug developers are continually seeking innovative strategies to enhance bioavailability, improve patient compliance, and expedite therapeutic outcomes. Pregastric absorption has emerged as a critical pathway to achieve these goals by enabling drugs to bypass gastrointestinal degradation and first-pass metabolism.

Join us for an insightful webinar as we explore the latest innovations in pregastric absorption. Learn more about advancements in buccal and sublingual delivery systems, the impact of permeation enhancers, and the role of PBPK modeling in predictive formulation design.

This session will provide a deep dive into how rapid-dissolving orally disintegrating tablets (ODTs) are transforming the landscape of drug development. Experts will also discuss how these trends are influencing the development of patient-centric formulations, all with the goal of improving therapeutic efficacy and patient experience.

Key Learning Objectives:

• Explore the latest formulation strategies, including the use of permeation enhancers and advanced ODT technologies, to improve the pregastric absorption of difficult-to-formulate drugs
• Learn how to apply PBPK modeling tools to simulate and predict drug absorption through the oral cavity, accelerating formulation development
• Understand how to create ODTs that are not only effective for pregastric delivery but are also more palatable and easier to administer, enhancing patient compliance

Speakers:

Jan Neelissen, PhD
Associate Director DMPK Advisory Services
Catalent

Jan Neelissen, PhD, serves as the associate director of DMPK advisory services. He has over 25 years of pharmaceutical industry experience in the field of DMPK. In his current role, he advises drug innovators in developing new therapeutics and designing tailored formulation, delivery, and manufacturing solutions. Neelissen is a trained biologist and holds a doctorate in pharmaceutical sciences from Leiden University.

Emilie Kimberley
Formulation Section Head Product Development
Catalent

Emilie Kimberley is a Formulation Section Head at Catalent in Swindon, United Kingdom. In her role, she supports formulation development for Zydis orally disintegrating tablets from feasibility studies to clinical supply at bench scale. With over 16 years’ experience within the pharmaceutical industry, she plays a key role in supporting the successful development of new Zydis products. Kimberley holds a BSc in pharmaceutical and chemical industries from the University of Paris Descartes and an MSc in industrial pharmaceutical sciences from the University of Manchester.

Afzal Mohammed, PhD
Professor of Pharmaceutics
Aston University

Afzal Mohammed, PhD, is a renowned professor of pharmaceutics and head of pharmaceutics at Aston University. He is an expert in particle engineering and paediatric formulation development, with funding from various bodies including INNOVATE UK, MRC, EPSRC, BBSRC and NC3R. He has presented research findings at major national and international conferences and was awarded a fellowship at the Academy of Pharmaceutical Sciences in 2017. His group has published over 100 publications and he serves as an associate editor for the International Journal of Pharmaceutics and BMC Pharmacology and Toxicology.

Register Free: https://www.pharmtech.com/pt_w/pregastric-absorption