Articles

Kidney transporter models are essential for identifying renal toxicity. Learn how immortalized primary renal tubule epithelial models stably expressing OAT1, OCT2 or OAT3 protein were tested for functionality.

Advanced renal models for toxicity screening

This paper outlines the basics of cleaning validation and discusses the support services you should seek from your critical cleaning products supplier to optimize your cleaning validation process.

Cleaning Validation for Pharmaceutical Manufacturing

In this white paper we look at reverse engineering existing drug products using Raman imaging.

Methods for deformulating drugs

Download the White Paper and learn how detailed characterization can guide successful development of gene therapy products.

Advanced Analytical Approaches for Accelerated Development of Gene Therapy Products

Discussion of the transfer of analytical HPLC methods from a Waters Acquity UPLC system to the Vanquish platform and highlights the impact of column thermostatting.

Transfer of an EP method for mebendazole

This application note demonstrates how sensitive UV detection provides quantitation of a genotoxic impurity at low ng/mL level.

Identity confirmation and accurate quantitation of a genotoxic impurity

The Cubis® II balance series was designed for customizable modularity, which means the user can choose from many hardware and software options for thousands of different configurations. Meet the requirements of the pharmaceutical industry with a combination of the MCA high-end 7” display and specific QApp pharma package, providing all features needed for a full pharma-compliant lab balance system.

Advanced Compliance for Use in Regulated Sectors | Cubis® II Pharma Compliant by Design


•	How alternating tangential filtration differs from other perfusion methods

•	The benefits of alternating tangential filtration


N-1 Bioreactor Perfusion Capability

Soft gel capsules are dosage forms that have an oblong and smooth casing that encapsulates a liquid. The soft gel casing (or gel-mass) is formulated by mixing together gelatin (or alternative material) with water, plasticizer and other ingredients. Historically, soft gel casings have been prepared in a batch mixing operation that takes many hours to complete.

A technical review of compounding, devolatilization, reactive processing, foaming and direct extrusion via twin screw extruders

Designing a formulation for a drug product calls for careful attention to both the physical and chemical properties of the active pharmaceutical ingredient. Find out how a pharmaceutical company can recognize both unfavorable drug substance properties and incompatibility between an API and its formulation to avoid potential risks to the patient and more.

All Whitepapers