Drug Development

Articles

Ashland introduces Klucel EXF Ultra HPC, a low friability, high strength binder. 

HPC Binder Designed for Small Tablets

Automated candle and pressure-plate filtration equipment for removing catalyst residues from API slurries are operated in a closed system.

Considering Alternative API Filtration Technologies

Cynthia A. Challener is a contributing editor to Pharmaceutical Technology.

Knowing the source and understanding the impact on CQAs is crucial to optimum drug formulation and processing.

Avoiding Excipient Variability

Andrew Johnson is analytical specialist with Gaylord Chemical Co, LLC.

Ashley Jones is analytical chemist with Gaylord Chemical Co, LLC.

In Karl Fischer analysis, sulfur trioxide can react with DMSO, invalidating test results. The authors evaluated different instruments and methods, described in this article, to minimize the impact on results.

Testing for Water in DMSO: Exploring Alternatives to Volumetric Karl Fischer Analysis

Large biopharmas, emerging biotechs, and CMOs are looking for novel ways to improve the productivity of biologics in a rapidly evolving biotherapeutics market.

The Search for Bioprocess Productivity Improvement

Cambrex’s expanded quality control laboratory supports generic API development.

QC Lab Extends Capabilities at Cambrex’s Milan Facility

Confidence in the quality systems and scientific competence of the API manufacturing team is essential.

Select Suppliers with Demonstrated Expertise to Avoid Sourcing “Bad” APIs

Rita Peters is the former editorial director of 

Pharmaceutical Technology, Pharmaceutical Technology Europe

Supplier vetting and monitoring-plus comprehensive testing-ensure quality of raw materials.

Locking Fraudulent Materials Out of the Supply Chain

Janssen’s Spravato (esketamine) gains approval with restricted distribution guidelines.

FDA Approves New Treatment for Depression

The acquisition will establish a clinical pipeline for Biogen of gene-therapy candidates in ophthalmology.

APIs and Excipients